Xenon Pharmaceuticals Inc.’s Post

We’re super excited to share that Abigail Graham, Associate Director, will be attending this year’s European Academy of Neurology Congress in Helsinki, Finland! Abigail is looking forward to joining discussions surrounding the recent developments in precision diagnosis, specifically the developments in headache from Teva Pharmaceuticals and AbbVie, and rare disease by Roche. She will also be joining talks surrounding how climate change contributes to the progression of neurological conditions such as sleep and stress. Keep an eye out for the team’s key insights from the congress, coming soon! #EANCongress2024 #EAN2024 #EAN #neurology #neuroscience #rarediseases #headache #climatechange #marketresearch #neurologicalconditions #sleep #stress #congress #attending #healthcaremarketresearch #marketresearch #research #pharmaceuticalmarketresearch #pharmamarketresearch #MRX

🔥 EAN 2024 Meeting Begins This Week! 🔥 The European Academy of Neurology Congress 2024, starting on June 29th, 2024, will spotlight groundbreaking research across key neurological fields. A total of 2,777 abstracts have been submitted, showcasing the latest research and advancements in neurology treatment and care. 🔴 Multiple Sclerosis (MS) leads the charge with the highest number of abstracts, followed by Parkinson's, Stroke, Migraine and Myasthenia Gravis 🔴 As the most discussed indication at this year’s EAN Congress, MS research is showcasing advances in diagnosis, treatment, and patient care. From innovative biomarkers to novel therapies, the scientific community is making tremendous strides in understanding and managing this complex neurological condition. For congress coverage or post-EAN intelligence question follow-ups, email us at 📥 [email protected] #EAN2024 #Neuroscience #Neurology #pharma #biotech #MulipleSclerosis #Migraine #ParkinsonDisease #MyastheniaGravis

Protein structures from #AI prediction using #AlphaFold2 guide prospective drug discovery for different neurological conditions. #BRET luminescence assays on the PHERAstar® FSX helped to reveal the G-protein signaling events involved for some of the top agonist hits identified for 5-HT2A serotonin receptors. Read the abstract here: https://lnkd.in/e893nbyt You can learn more about the study here: https://lnkd.in/eF6FcB5z #BRET #machinelearning #drugdiscovery #neurology #compchem #microplatereader #platereader #laboratoryequipment #laboratorywork #wearebmglabtech

From basic #research to #drugdiscovery every step matters for the development of life saving #therapeutics & treatment against #neurodegenerative diseases & other #neuropathies. Progress faster by selecting the appropriate R&D #reagents & devices here: https://lnkd.in/e3Atmy8V #neuroscience #neurology #neuroresearch #drugtheraputics #bioscience #lifesciences #biotech #biopharma #biologistics #ionchannels #neurodegenerators #nanobodies #cellculture #antibody #antibodies #assays

Join us at #ASGCT24, where we will showcase our neurology-focused pre-clinical pipeline, including data supporting innovations in zinc finger epigenetic regulation, advances in AAV capsid engineering, and discovery of our next-generation integrase technology.   Details here on our 20 abstracts that will be presented, https://bit.ly/3wf1Aai #genomemedicine #neurology #epigenetics #zincfinger

Alcohol appears to have dose-dependent effects. Excess intake is clearly detrimental, but use and abuse are entirely different. The latest recommendation in oncology is that zero intake is best. In the real world, people have more than cancer to consider though. Add the study below that shows less abnormal protein aggregation in the brain to your alcohol pro/con list. Perhaps we will be able to individualize our recommendations for alcohol intake someday.

SPU-16, Silo's novel homing peptide targeting #multiplesclerosis (#MS), is being developed in collaboration with the University of Maryland, Baltimore (UMB). The drug is designed to cross the blood-brain barrier and target damaged tissue and inflammation. Learn more about SPU-16, which has to potential to transform treatment for those suffering from the most widespread disabling neurological condition in young adults: https://bit.ly/40vPhAN #Science #Biotech #Biopharma #Neurology

💊 𝗦𝘂𝗰𝗿𝗮𝗹𝗳𝗮𝘁𝗲 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗣𝗲𝗮𝗿𝗹𝘀 💊 ✅ medicine used to treat heartburn and acts as cytoprotectice. ✅ dose is 2g twice a day or 1g four times a day, meaning every 6 hours. ✅ contains aluminum, so its most common side effect is constipation by reducing bowel movement. ✅ interfere with some medications and reduce their absorption, such as: Levofloxacin, Digoxin, Warfarin, Theophylline, and others. ✅ to reduce this interference, they must be separated by at least two hours. #pharmacology #medicine #MedEd #medicine #MedicalStudents #pharmacology #PharmEd #ICU #emergencymedicine #neuroscience #Neurology #departmentofPharmacy

As we advance our work to the clinic to bring patients therapeutic options for #neurodegenerativediseases, we at Muna Therapeutics have serious fun, every day - check out the video clip below! #muna_tx #neuroscience #neurodegeneration #alzheimersdisease #parkinsonsdisease #multiplesclerosis #biotech #neurology

Alcohol consumers with liver pathology rarely display α-synuclein pathology A study examining postmortem brain and liver tissue from 100 individuals found a negative correlation between alcohol-induced liver damage and α-synuclein pathology in the brain. Individuals with severe liver damage were more likely to have Alzheimer's type II astrocytes, but dementia was less common in this group. These findings suggest that alcohol consumption may protect against Parkinson's disease although the sample size is small. This study should be replicated in other populations as well. The article was published in Acta Neuropathologica: https://lnkd.in/eR7AYj9B #genetics #genomics #precisionmedicine #genomicmedicine #brain #neurology #neurodegeneration #neuroscience #alzheimer #parkinson #als #ftd #alcohol #addiction #liver #hepatology #clinicalresearch #biomarkers #biotechnology #innovation #research #science #sciencecommunication