Sophia Delatour’s Post

Infections and immunity grant from the Medical Research Council (MRC) now open. To be eligible for funding to support a research program focusing on infections and immunity, you need to be employed at a research institution that can apply for Medical Research Council (MRC) funding. It is essential to have a track record of successfully securing funding and conducting research. There is no specified limit on the amount of funding you can request, with most applicants seeking £1 million or more. Typically, we cover up to 80% of the total economic cost of your project. The duration of your program can extend up to five years. Participation in the pre-application phase is mandatory, and only selected applicants will proceed to the full application stage. This funding opportunity is available continuously, with application deadlines falling in January, May, and September. https://buff.ly/3TZbFkH At Capti Innovation our mission is to make grant funding more accessible. Every year, we help hundreds of companies save time, win funding and accelerate growth by leveraging our extensive expertise in funding opportunities. Email us for more information [email protected] #funding #investing #fintech #technology #sustainability #growth #cybersecurity #environment #food #automation #automotive #recycling #nutrition #medicine #robotics #farming #augmentedreality #neuroscience #grants #ukgrants #startupgrants #businessgrants #ukgovernmentgrant #sme #smegrant #businessfunding #smefunding #technologygrant #innovationgrant #capti #captiinnovation #gamechanging #gamechanginginnovation #disruptiveinnovation #smartgrant #ai #manufacturing #sustainable #innovation #telecoms #semiconductors #business #IUK #InnovateUK #SmartGrant #InnovateUKfunding

Tezted presents: Recent high-quality scientific studies. This week's paper is Estrada-Mendizabal et al 2023. 🚨 Urgent Health Alert: 🚨 An unprecedented rise in rickettsiosis cases is occurring in Nuevo Leon (NL), Mexico. Since January 2022, 73 cases have been identified, compared to just 13 cases in 2021. Despite multidisciplinary efforts, the current outbreak is ongoing, and we need your attention! 🔬 Study Method: A descriptive study evaluated patients' demographic, clinical, and laboratory characteristics in NL with confirmed rickettsiosis from Jan 2022 to March 2023. Cases were confirmed through positive real-time PCR followed by whole-genome sequencing or seroconversion by IFA assay. 📊 Key Results: 73 cases were confirmed, with an incidence of 1.2 cases/100,000 inhabitants (compared to 0.2/100,000 in 2021). Median age was 11 years, with 57.5% females. Most patients (90%) required hospitalization, all had tick exposure within two weeks before symptoms. R. rickettsii was predominant (93.1%). Common symptoms: fever (100%), headache (77%), abdominal pain (71%). High mortality (63%) documented. 💊 Treatment: Early treatment with doxycycline is crucial. 52 patients were treated, with a median time-to-treatment initiation of 4 days. Doxycycline treatment (p=0.05) and TTI ≤ 24 hr (p=0.01) were associated with survival. 🔍 Conclusion: The current outbreak of rickettsiosis in NL has led to high morbidity and mortality, especially in children. Efforts are underway to control the outbreak, including vector control strategies, education of healthcare personnel, and public awareness campaigns. 👩⚕️ Takeaway: Clinicians on the Mexico-United States border should maintain a high suspicion index for rickettsiosis among patients with compatible symptoms and consider early antibiotic treatment to reduce mortality risk. Stay informed, stay safe! #HealthAlert #RickettsiosisOutbreak #NuevoLeon #StaySafeNL #PublicHealth #Rickettsia #Mexico #DiseasePrevention #HealthAwareness #TickBorneDisease #TICKPLEX www.labomedishi.com.mx www.tezted.com

Emma McGrath attended the short course Technology Assessment for Rare Diseases on Sunday as part of #ISPOREurope 2024. She captures her learnings below. Speakers: Hwee-Lin Wee -Lin Wee, PhD joshua byrnes , PhD Diana Beatriz Bayani, MSc, PhD Session 1: Overview of rare diseases Looking at the case study of Spinal Muscular Atrophy (SMA) Limited research and development to receiving treatments for rare diseases such as regulatory barriers, recruitment and unpredictability. The European Organisation for Rare Diseases (EURORDIS) and the Orphan Drug regulation initiatives to encourage R&D for rare diseases. Singapore’s approach to finance rare diseases addressing the need for an appropriate financing framework, that is both sustainable and will prevent a schism between those who can afford precision medicine and those who cannot. Session 2: Comparing the Experiences of England and Singapore. Key features of rare disease policies, HTA pathways and funding Case Studies: Comparing the experiences of England and Singapore Implications for future policy and practice Session 3: Economic Evaluation of rare diseases Types of economic evaluation Cost-effectiveness planes and quantifying the uncertainty Spotlight on extrapolations and their uncertainty over time Session 4: Multicriteria Analysis (MCDA) requires the aggregation of criteria into a single expression of value. MCDA has been used to organise data and questions relevant to the development of clinical practice guidelines (CPG) for a rare genetic condition, Prader-Willi syndrome (PWS) Pros of MCDA are how it Improves transparency, promotes consistency, Does not replace judgement Cons of MCDA: Requires careful design considerations and is time consuming. #shortcourse #ISPOR #learning #raredisease #economicevaluation #multicriteriaanalysis

Great to see that Coronary Artery Disease (CAD) Polygenic Risk Score (PRS) is also cost-effective in Australia. Two years ago, we demonstrated that CAD PRS is cost-effective in the US. https://lnkd.in/dtjzANUf Despite different health systems, costs, and dynamics, the outcome remains the same: CAD PRS saves and improves lives and is economically sustainable. #precisionmedicine #prs #cad #polygenic #costeffectiveness

Dasman Diabetes Institute, in collaboration with Harvard University, announced the findings of a study revealing a link between high temperatures, dust storms, and increased hospital admissions for diabetic patients in Kuwait. Researchers collected daily dust samples from 2017 to 2019, alongside temperature data and hospital admissions records. The study found a significant rise in hospitalizations among diabetic patients with higher temperatures and more frequent dust storms. The researchers concluded that heat stress and dust exposure can worsen health problems in diabetics by impairing glycemic control. The findings highlight the need to consider environmental factors like air quality in public health policies. Dasman Diabetes Institute, established by the Kuwait Foundation for the Advancement of Sciences, remains dedicated to combating diabetes through advanced research, prevention, education, and treatment. #KFAS #diabetes #research

⭐ ⭐ We are delighted to reach UK top 20 status for 14 days’ recruitment to the GenOMICC study, thanks to the great work of our fabulous Critical Care Research Team.⭐ ⭐ When most people become unwell from an infection, they have a mild case of the illness. However, some people become so unwell that they need to be in critical care. The GenOMICC study is a huge international study that is trying to identify the specific genes that make people susceptible to becoming critically unwell. Once the genes that make us high risk of becoming very poorly have been identified, new treatments can be investigated that will target these genes. 💙Research is a vitally important part of WUTH’s strategy to provide leading healthcare to our local population because it allows patients to receive new therapies. 💙 #Research

This afternoon we are going to talk about different types of vWD breaking some common beliefs and assumptions on related symptoms EHC - European Haemophilia Consortium

NEW RESEARCH PUBLISHED cc Lifesten Health I am thrilled to announce that our research titled "EXAMINING THE COST BENEFIT ANALYSIS FOR TRADITIONAL AND TECHNOLOGICAL APPROACHES TO CARDIOVASCULAR SCREENING IN RWANDAN HEALTHCARE: A MIXED-METHODS STUDY WITH A FOCUS ON LIFESTEN HEALTH" has been published in the ISAR Journal of Medical and Pharmaceutical Sciences! Cardiovascular diseases (CVDs) are a major global health concern, and our study, co-authored with Ndoli Peace, RDN, MGHD and Gabriel Oke, delves into the cost-effectiveness and efficiency of traditional vs. tech-enabled cardiovascular screening methods in Rwanda. Our findings highlight the potential of technology-based screening via Lifesten Health in offering greater efficiency with minimal equipment and training requirements, while also addressing the challenges of digital illiteracy and material shortages in conventional methods. Investing in digital literacy and enhancing healthcare provider training are key to reducing the burden of CVDs in Rwanda. A dual-focused approach could significantly improve health outcomes and save lives. Read more about our groundbreaking research and its implications for the future of cardiovascular health screening! Read the paper here https://lnkd.in/d74GnPjM #Research #CardiovascularHealth #HealthcareInnovation #DigitalHealth #LifestenHealth #Rwanda #MedicalResearch

Laboratory services are an essential component of a high-quality healthcare system for detecting diseases with public health implications. Patient satisfaction with laboratory services is critical to giving appropriate therapy. The study sought to determine the level of satisfaction among patients with lab services at secondary-level facilities. The current study at two secondary-level hospitals in Bangladesh's north region found that over sixty percent of respondents were satisfied with laboratory services, which were measured using indicators of basic laboratory services, laboratory physical facilities, and laboratory personnel approach. This study emphasized the need to enhance the quality of laboratory services provided in secondary-level healthcare facilities to satisfy patients' expectations. To access the full article, go to: https://lnkd.in/gWePJmCM Feel free to cite this article: Hossen MP, Islam ANMS, Shohid S, Sen RR, Manzil MJ, Haque M, Dey C, Naznin MB, Begum D, Bhuiya MT and Farhana N (2023). Patients’ satisfaction towards laboratory services at secondary level hospitals. International Journal of Natural and Social Sciences, 10(2): 37-46. DOI: 10.5281/zenodo.10575770

Great work! While climate change and dust storms have become a part of life in our region, diabetes doesn’t have to be. It’s a disease we can control—and in some cases, even put into remission! At Dasman Diabetes Institute (DDI), multiple clinical trials are underway or about to launch, focused on helping people manage and reverse diabetes. One of our key studies targets individuals with uncontrolled type 2 diabetes who are currently on insulin therapy. DDI is proud to be at the forefront of the fight against diabetes, working to bring new solutions and hope to those affected. Stay tuned for more updates!Kuwait Foundation for the Advancement of Sciences (KFAS) Dasman Diabetes Institute #Diabetes #HealthCareInnovation #ClinicalTrials #Type2Diabetes #DiabetesResearch #Remission #DiabetesCare #DDI #Kuwait #PublicHealth #MedicalResearch #FightDiabetes #PreventDiabetes