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Sanofi’s commitment to transforming drug discovery, development, and delivery is nothing short of visionary. Following its recent earnings report, Sanofi made bold moves to focus solely on innovative pharmaceuticals, doubling down on internal R&D while spinning off its consumer division. CEO Paul Hudson’s dedication to science is setting Sanofi apart in an era of looming exclusivity losses across the industry. His strategic decision to strengthen in-house R&D and champion talents like Dr. Frank Nestle and Dr. Houman Ashrafian aims to drive groundbreaking therapies, with AI as a cornerstone. This long-term focus may have surprised the market, but it’s a powerful commitment to revolutionizing medicine and creating lasting impact. #Pharmaceuticals #Sanofi #DrugDiscovery #Innovation #AIDriven #R&D #PaulHudson #BioCenturySummit #HealthcareInnovation #Biotechnology #ClinicalResearch #TransformingHealthcare https://lnkd.in/gENwXaSV

Can big pharma sustain growth through R&D alone? The data says no, with almost half of leading companies failing to generate commercial value that compensates for the enormous R&D costs.    That’s the conclusion of a recent analysis of R&D productivity from Schuhmacher and colleagues, who looked at the financial inputs, outputs and outcomes of 16 of the biggest pharma companies (https://lnkd.in/ecedzfB8).    The findings support the well-known fact that R&D productivity (the ratio of commercial value of new drugs to the cost of drug discovery and investment) is one of the biggest challenges for any pharmaceutical company.     So what can be done to improve the efficiency and effectiveness of R&D, and ultimately lead to more great drugs reaching patients?     As suggested in another analysis by Roland et al. (https://lnkd.in/edbdruSG), there is no ‘one size fits all’ solution to improving R&D productivity. However, some companies may be able to save over $1 billion in cost per approval by improving their mid or late-stage success rate, dramatically boosting R&D productivity.     At Weatherden, we are committed to increasing our clients’ probability of technical and regulatory success. We won’t let inefficient processes or poor decision-making be the reason why a great drug never reaches the clinic.     We’re able to draw on extensive clinical, scientific and drug development expertise across a wide range of indications and modalities to guide companies through the complex landscape of drug development efficiently and cost-effectively.     Whether it’s helping you move towards value-based portfolio management, using real-world data to enable better R&D, or adjusting your strategy to focus on drugs with broader indications, we’ll help you navigate the best pathway to generate a definitive clinical data package that supports your commercial decision-making.     We’ve demonstrated this repeatedly over the last 7 years by improving our clients’ probability of success to over 65% in early development vs. an industry average of 29%. During that time, our mission has stayed the same — support our clients to give every great drug the best chance of clinical success and make a difference to patients’ lives.    If you’d like to learn more, head to our website: https://lnkd.in/d2DY3WmQ     #DrugDiscovery #DrugDevelopment #R&D #R&DProductivity #ResearchandDevelopment #Pharma   

The Pharmaceutical Innovation & Invention Index 2024 webinar, hosted by industry experts at IDEA Pharma | From R&D to RxD, highlights the importance of innovation and invention in the pharmaceutical industry. The discussion includes company strategies, decision-making processes, and the application of AI, providing a comprehensive overview of the industry’s current landscape. A few of the key takeaways from this webinar are: Innovation Index: Innovation is the return on invention and the creation of meaningful value. The Innovation Index evaluates companies using clinical, regulatory, and commercial metrics, providing a comprehensive view of the industry’s innovation landscape. The webinar also highlights the PIII Innovation Methodology, evaluating pharmaceutical companies across multiple dimensions. Balancing pipeline phases ensures a steady flow of innovative therapies to meet market demands and replace expiring patents. Novo Nordisk leads the Innovation Index, showcasing commitment with innovative therapies like CagriSema, currently in Phase 3 development for Type 2 diabetes and obesity. Strategic Partnerships and Invention: Strategic partnerships and well-defined strategies are crucial for maintaining high levels of invention. Johnson & Johnson leads the Invention Index, reflecting remarkable growth in revenue and R&D investment. AI-enhanced decision-making accelerates the early stages of drug discovery, allowing companies to pursue more innovative paths with limited resources. The webinar also sheds light on the Freshness Index which measures a company’s ability to renew its product portfolio, ensuring sustainability and a competitive edge.  I believe the future of pharma lies in fostering environments where inventive science meets innovative development and commercialization strategies. While inventing groundbreaking therapies remains an essential goal, the art of adding value to these breakthroughs is equally crucial. It's not just about creating new drugs, but about reimagining how we can deliver better outcomes to patients and healthcare systems. Visit the link for the full webinar report: https://lnkd.in/dmcXum2s #Pharma #Innovation #LifeSciences #DrugDiscovery #HealthcareInnovation

How Smart Manufacturing is Shaping Pharma's Future Jitendra Mishra, SVP, VP-CIO, Akums Drugs& Pharmaceuticals Ltd From virtual doctor-patient connections to a seamless global supply chain, digital innovation is transforming personalized care at every step. Read more: https://qrcd.org/7V20 #smartmanufacturing #pharmacompanies #ClinicalResearchIndustry #personalizedhealthcare #digitaltransformation #digitalmanufacturing #emergingtechnology #smartmanufacturing #emergingtechnology

The NC pharmaceutical industry #growth and #innovation has been nothing but astonishing since I moved here. While this is not a comprehensive list, I wanted to highlight some of the major expansions and builds in just the last few years for my friends who may have missed them (Note: Some information in this post may be out of date - information sourced from Fierce Pharma and respective company websites). Novo Nordisk: $𝟐𝐁 investment to build an Active Pharmaceutical Ingredient (API) facility. This facility aimed to increase production capacity for diabetes treatments. + Novo Nordisk: Additional $𝟒.𝟏𝐁 investment to build a second fill-finish manufacturing plant, doubling the combined footprint of Novo Nordisk's existing facilities in the state (~3,500 𝑗𝑜𝑏𝑠 𝑖𝑛 𝑁𝐶 𝑡𝑜𝑡𝑎𝑙). Eli Lilly and Company: over $𝟏𝐁 investment in a new injectable product and device manufacturing facility in Concord, North Carolina. (~600 𝑛𝑒𝑤 𝑗𝑜𝑏𝑠). + Eli Lilly and Company: $𝟒𝟓𝟎𝐌 investment in its manufacturing site in Research Triangle Park (~100 𝑛𝑒𝑤 𝑗𝑜𝑏𝑠). FUJIFILM Diosynth Biotechnologies: $𝟏.𝟐𝐁 in expansion of its end-to-end biomanufacturing facility in Holly Springs. This brought the total investment in the plant to more than $𝟑.𝟐𝐁 (~680 𝑛𝑒𝑤 𝑗𝑜𝑏𝑠). Amgen: $𝟓𝟓𝟎𝐌 investment in a greenfield manufacturing facility in Holly Springs for biologics and other medicine production. Resilience: $𝟐𝟐𝟓𝐌 aimed at scaling up production capacity. SCHOTT Pharma: $𝟑𝟕𝟏𝐌 in a new prefilled syringe manufacturing facility in Wilson, North Carolina (~400 𝑛𝑒𝑤 𝑗𝑜𝑏𝑠). Fresenius Kabi: $𝟏𝟎𝟎𝐌 expansion of its pharmaceutical manufacturing facility in Wilson, increasing production capacity for generic drugs in prefilled syringes (~450 𝑛𝑒𝑤 𝑗𝑜𝑏𝑠). Pfizer: $𝟔𝟎𝟎𝐌 investment in expanding its gene therapy manufacturing facility at its Sanford campus to improve clinical and commercial-scale manufacturing capabilities. Kyowa Kirin International plc. Kirin: $𝟓𝟑𝟎𝐌 to establish a biologics manufacturing facility in Sanford (~100 𝑛𝑒𝑤 𝑗𝑜𝑏𝑠). These significant investments in North Carolina foreshadow its growing role as a hub for biotech manufacturing and innovation. I'm glad I get to be a part of it, and I'm equally excited to see what comes next! #NC #Biotech #PharmaceuticalManufacturing

Recent insights from Dr. Dmitry Reykhart, Chairman of the Board of Directors at Forte Pharma Fund regarding the prevailing trends within the #biopharmaceutical sector and the factors driving its recovery. Dr. Reykhart discusses the significant shift in focus from #Covid19 treatments to the booming #obesity market, indicating a strategic redirection of interests within the industry. Furthermore, the article discusses the proactive measures adopted by #BigPharma names to mitigate the impacts of the #LossofExclusivity trend and highlights the sector's resilience amidst evolving market dynamics. For a comprehensive analysis of 'What's Driving Big Pharma's Recent Market Performance?', please refer to the link provided below. https://lnkd.in/ejxuWiYz Marketing | Capital at risk | For professional investors #pharma #BigPharma #Forbes #ThoughtsOnTheMarket

𝗚𝗹𝗼𝗯𝗮𝗹 𝗣𝗵𝗮𝗿𝗺𝗮𝗰𝗲𝘂𝘁𝗶𝗰𝗮𝗹 𝗥&𝗗 𝗦𝗽𝗲𝗻𝗱𝗶𝗻𝗴 (𝟮𝟬𝟭𝟰-𝟮𝟬𝟮𝟴) 💸 In 2022, global pharmaceutical R&D spending reached $244 billion, up from $137 billion in 2012. This investment covers all stages of drug development, with oversight from agencies like the FDA, particularly during pre-clinical phases. 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 𝗣𝗿𝗲𝘀𝘀𝘂𝗿𝗲 Pharmaceutical companies face intense pressure to innovate due to limited drug patent protection, driving high R&D spending and a shift towards specialty drugs to maintain market share. 𝗞𝗲𝘆 𝗧𝗿𝗲𝗻𝗱𝘀 Outsourcing: More R&D activities are being outsourced to CROs to reduce costs. 𝗕𝗶𝗴 𝗗𝗮𝘁𝗮: Integration of big data is enabling predictive modeling for safer, more efficient drugs. 𝗧𝗲𝗰𝗵 𝗖𝗼𝗹𝗹𝗮𝗯𝗼𝗿𝗮𝘁𝗶𝗼𝗻: Partnerships with tech firms are increasing due to the growing importance of real-world evidence. 𝗥&𝗗 𝗘𝘅𝗽𝗮𝗻𝘀𝗶𝗼𝗻: Companies like Roche, Pfizer, Johnson & Johnson, and Novartis are expanding their R&D efforts, focusing on oncology, immunology, and personalized medicine. R&D spending is expected to continue rising through 2028, driven by the ongoing pursuit of innovation and new therapeutic breakthroughs. #PharmaInnovation #RDTrends2024 #DrugDevelopment #FutureOfPharma

🚀 Emerging Trends in Pharma: A Deep Dive into Innovation & Technology 🧬 The pharmaceutical landscape is evolving rapidly, with groundbreaking technologies reshaping healthcare's future. In our latest TrendFeedr report, we delve into the exciting world of specialty pharmaceuticals, biosimilars, and digital transformation in the pharma industry. 🔍 Key Insights: - Specialty pharmaceuticals and biosimilars are paving new paths in treatment. - Digital pharmaceuticals are at the forefront, transforming patient care. - Investment in pharma R&D soared to $244 billion in 2022, highlighting industry growth. 📈 Why This Matters: Staying informed helps in strategizing and aligning with the industry’s direction. 🔗 Explore the full report for detailed insights: https://lnkd.in/eir_W8iW #Pharma #Innovation #HealthcareTechnology #TrendFeedr #DigitalTransformation

𝐄𝐧𝐝-𝐭𝐨-𝐄𝐧𝐝 𝐃𝐫𝐮𝐠 𝐃𝐞𝐯𝐞𝐥𝐨𝐩𝐦𝐞𝐧𝐭 𝐒𝐨𝐥𝐮𝐭𝐢𝐨𝐧 𝐌𝐚𝐫𝐤𝐞𝐭 𝟐𝟎𝟐𝟒-𝟐𝟎𝟑𝟐: 𝐆𝐥𝐨𝐛𝐚𝐥 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐑𝐞𝐩𝐨𝐫𝐭📈 𝐑𝐞𝐪𝐮𝐞𝐬𝐭 𝐟𝐨𝐫 𝐒𝐚𝐦𝐩𝐥𝐞 𝐂𝐨𝐩𝐲: https://lnkd.in/dKy6eJdm The End-to-End Drug Development Solution Market is poised for substantial growth, driven by advancements in personalized medicine, AI-driven analytics, and increasing demand for efficient pharmaceutical solutions. In 2023, the market was valued at approximately $95 billion USD and is projected to reach $185 billion USD by 2032, growing at a compound annual growth rate (CAGR) of 7.8%. This expansion is fueled by the need for streamlined drug discovery, regulatory compliance, and robust clinical testing across various regions, especially in North America and Europe, which are key innovation hubs. Our latest report provides in-depth insights on both quantitative and qualitative aspects of the End-to-End Drug Development Solution Market. It includes analysis on leading manufacturers, comprehensive regional analysis, product types, and applications. The report highlights key companies, offering profiles with product insights and market share estimates of top competitors in 2024. 𝐁𝐲 𝐓𝐲𝐩𝐞: Small Molecule Drugs, Biologic Drugs 𝐁𝐲 𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧: Drug Discovery, Clinical Trials, Regulatory Compliance, Manufacturing, Post-Marketing Surveillance 𝐁𝐲 𝐑𝐞𝐠𝐢𝐨𝐧: North America, Europe, Asia-Pacific, South America, Middle East & Africa 𝐁𝐲 𝐊𝐞𝐲 𝐏𝐥𝐚𝐲𝐞𝐫𝐬: Pfizer, AstraZeneca, Roche, GSK, Sanofi, Merck Group, Novartis, AbbVie, Johnson & Johnson, Takeda, Amgen, Boehringer Ingelheim, Eli Lilly and Company, Gilead Sciences, Bristol Myers Squibb, Teva Pharmaceuticals, Biogen, Abbott, Lonza, Labcorp, Charles River Laboratories, ICON plc, WuXi AppTec, Parexel, IQVIA, Medpace, Syneos Health, Parexel, KCR, Almac Group, Eurofins Scientific Finland Oy, GenScript, Celltrion Inc, FUJIFILM Diosynth Biotechnologies, WuXi Biologics, Catalent Pharma Solutions #drugdevelopment #biotech #pharmaceutical #clinicaltrials #marketresearch #healthinnovation #biologics #globalhealth #healthcaretech #drugdiscovery #endtoendsolutions #cagr #biopharma #marketgrowth #innovation #personalizedmedicine #globalmarket #europebiotech #northamericabiotech #asia药

With Big Pharma's R&D spend growing by 6% over the last 20 years, R&D productivity continues to be the industry’s grand challenge. This study assessed the R&D productivity of 16 leading pharmaceutical companies by sales (2020) to gain insights into the ability to commercially profit from R&D. By reviewing corporate data as well as assessing and dissecting the state-of-the-art, R&D productivity remains a core challenge of big pharma companies. To combat this, Open innovation (OI) is a widely used R&D model for the research-based pharmaceutical industry that has the capability to accelerate time to value. By opening up opportunities and challenges to the Collective Intelligence of a mapped ecosystem of existing partnerships or the wider world, R&D products are 3x more likely to be filed/marketed, thus reducing costs of extended development and quickening time to market. To gain more insight on how Novartis, AstraZeneca & Bayer have opened their R&D to ecosystems, drop a comment or feel free to reach out. #openinnovation #RandD #collectiveintelligence Jack Sanderson