Professor of Natural Products Chemistry, Food Chemistry, Phytotherapy and Pharmacognosy, Pharmacognosy Department, Faculty of Pharmacy, Ain-Shams University, Cairo, Egypt.
Novel Mechanism Supports Antitumor Response and T-cell Survival https://lnkd.in/da4ksju2
Initial data from a phase 1 study show promising radiation dosimetry results with 177Lu-rhPSMA-10.1 injection in patients with mCRPC. https://lnkd.in/egTPctpp
Director of Bioinformatics | Cure Diseases with Data | Author of From Cell Line to Command Line | Data Science | Educator | Cloud Computing | Dana-Farber | MD Anderson | Join 34K followers on Twitter @tangming2005
Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens https://lnkd.in/e2T9W5nH
Associate Dean for Oncologic Sciences, Warren Alpert Medical School, Brown University, Providence, RI
STING licensing of type I dendritic cells potentiates antitumor immunity https://lnkd.in/eVMZHjKG
Tumor-Associated Monocytes Reprogram CD8+ T Cells into Central Memory-Like Cells with Potent Antitumor Effects https://lnkd.in/gjrV8bvt
HIF-2α-dependent induction of miR-29a restrains TH1 activity during T cell dependent colitis https://lnkd.in/gwCmTaxP
MD(Anesthesia,Urgent Care)UrologyResearch UPENN AI,HC-AI,QCAI,PAI,XR SAI/Robotics/NeuroAI/Multiomics/Energy/ReverseAging Open for AIStartups seeking strategic investments. HI-HSI>AI-AGI-ASI/HI-HSI<AI-AGI-ASI(?)
<<mRNA encapsulated in LNPs>>
TGF-β broadly modifies rather than specifically suppresses reactivated memory CD8 T cells in a dose-dependent manner https://lnkd.in/gYV3rwq8
Regulation of Foxo1 expression is critical for central B cell tolerance and allelic exclusion https://lnkd.in/gfrWqfpG
Our recent work was published in Head and Neck! M2 polarization was associated with EGFR overexpression ! Reprogramming M2 could be a therapy target in p16 negative OPC. https://lnkd.in/gUTcz4Vh
