Labena Slovenia’s Post

Innovation never stops! Quickly resolve tissue heterogeneity and the complexity of microenvironments with the NanoString GeoMx Digital Spatial Profiler (DSP), the most flexible and robust spatial multiomic platform for analysis of FFPE and fresh frozen tissue sections. GeoMx profiles expression of RNA and protein from distinct tissue compartments and cell populations with an automated and scalable workflow that integrates with standard histology staining. Contact one of our #BioChain experts today to learn more about 570 proteins IPA panel co-detection with whole transcriptome on GeoMx DSP spatial biology platform for biomarker discovery and hypothesis testing. https://bit.ly/47PDqkV #spatialtranscriptomics #spatialbiology #histology #spatialresearch #biotech #FFPE #tissues

𝐂𝐞𝐥𝐥 𝐃𝐢𝐯𝐢𝐬𝐢𝐨𝐧 𝐢𝐧 𝐀𝐧𝐢𝐦𝐚𝐥 𝐂𝐞𝐥𝐥𝐬: 𝐀 𝐌𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐢𝐜 𝐉𝐨𝐮𝐫𝐧𝐞𝐲 🧬 In a recent study, normal pig kidney epithelial cells (LLC-PK1 line) were observed undergoing mitosis using laser scanning confocal microscopy. These cells were labeled with mEmerald fluorescent protein fused to microtubule EB3, a protein binding to the positive ends of microtubules, and mCherry fused to human histone H2B, highlighting the chromosomes. One of the most distinguishable phases of mitosis is metaphase. During this critical stage, chromosomes attach to the kinetochore microtubules and align in a single plane, known as the metaphase plate, midway between the spindle poles. The kinetochore microtubules exert tension on the chromosomes, causing them to move back and forth in rapid, erratic motions. This dynamic setup prepares the spindle-chromosome complex for the next pivotal event: the separation of daughter chromatids. Metaphase, a crucial stage in mitosis, occupies a significant portion of the cell division cycle. Understanding this phase is essential for comprehending the intricate mechanisms of cellular division and the maintenance of genetic integrity. #CellBiology #Mitosis #Microbiology #Microscopy #CellDivision #ScientificResearch #LifeSciences #Genetics #Biotech #STEM

Don't let complex 3D structures hinder your research. Our latest blog post provides essential tips and techniques to achieve stunning results. Discover how to: 1. Overcome the challenges of staining 3D structures 2. Adapt imaging techniques for 3D cultures 3. Choose the right stains for your specific needs https://lnkd.in/gJnixMth #3Dcellculture #organoids #spheroids #staining #imaging #biotechnology #research #science #lablife #cellbiology #translationscience #benchtobed #cellstaining

🌟 Exciting Kickoff to the Next GynGeneration Symposium! 🌟 🔜 Introducing the first session of «Bridging RNA Biology and Therapy: Exploring the Frontiers of Advanced Medicine» that will take place on the 9th and 10th of October 2024. 🧬 Our initial session is called «Functional ncRNAs and RNA modifications in development and disease» and will be divided into two sections. The first one named Noncoding RNA will explore the significant roles these RNAs play in physiology, development, and disease. The second one, RNA Modifications, will delve into how RNA modifications introduce functional diversity and regulate gene expression, influencing RNA structure, interactions, and metabolism. We will discuss how these modifications enable rapid responses to environmental changes and their implications in disease pathogenesis, including cancer. 🔍 Explore the whole program here and don’t forget to submit your abstracts before September 2nd, 2024: https://lnkd.in/drymNztB #RNABiology #Therapy #RNA #AdvancedMedicine #RNAInsights #ScienceEvent #CIMA #Pamplona #SymposiumProgram #Innovation #Research

The Human Cell Atlas maps human tissues and systems throughout life and provides methods to handle single-cell data. This Nature article discuss its potential impact on our understanding of human biology. #research #biology #innovation https://lnkd.in/ePWcp4Rd

🔬 HeLa cells have great value for different experimental studies. ⬇️ The video below was taken by Sabine Reither, European Molecular Biology Laboratory, EMBL, and shows mitosis in live HeLa cells stained for histone 2B-mCherry (magenta), GFP-tubulin (green) and GFP-tubulin (white, deconvolved). 💡 These processes were imaged with the Bruker InVi SPIM Lattice Pro and is a great example of the benefit of using light-sheet microscopy for investigating 3D cell cultures. #microscopy #lifesciences #biology #WomenInSTEM

𝗦𝗶𝗻𝗴𝗹𝗲-𝗰𝗲𝗹𝗹 𝗮𝗻𝗱 𝘀𝗽𝗮𝘁𝗶𝗮𝗹 𝘁𝗿𝗮𝗻𝘀𝗰𝗿𝗶𝗽𝘁𝗼𝗺𝗶𝗰𝘀 𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗼𝗳 𝗺𝗲𝗴𝗮𝗸𝗮𝗿𝘆𝗼𝗰𝘆𝘁𝗲𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗵𝗲𝗮𝗹𝘁𝗵𝘆 𝗯𝗼𝗻𝗲 𝗺𝗮𝗿𝗿𝗼𝘄 We're excited to hear from Postdoctoral Researcher, Dr Sonia Fonseca, at #EISingleCell24 later this year. As part of the Wojtowicz Group at EI, Dr Fonseca will be discussing how #singlecell resolution is key to providing biological insights into the cellular heterogeneity of #megakaryocytes. 🎫 Don't forget to register to join us: https://okt.to/Gc3AxZ #SpatialTranscriptomics #CellularGenomics #platelets #biology

Are you interested in learning the techniques available when applying #SEM to your biological research 🤔 In this webinar, we will discuss the range of techniques available to biologists and provide examples from different types of samples, from plants and tissues to cells and organelles, covering medical applications and cell biology 👉 https://okt.to/YeZWst #BiologicalResearch #Biologists #CellBiology

🌀Catch a glimpse into the radiance of single and multiplex immunofluorescence slides, capturing the essence of cellular complexity...! Connect with us to explore the fascinating world of cellular imaging..🔬 #Immunofluorescence #Microscopy #Research #Biology #CellBiology #Fluorescence #Technology #Innovation

I'm excited to share that I've completed the Introduction to Nanopore Sequencing course offered by Oxford Nanopore Technologies! 🧬🧪 This course provided a comprehensive overview of nanopore sequencing technology, including relevant applications, workflows, and resources. I'm eager to apply this knowledge in my work and explore the potential of this cutting-edge technology in molecular diagnostics and genomics. Oxford Nanopore Technologies #MoleculDiagnsotics #Genomics #IBMS