Reflecting on BioTechX 2024 in Basel! 🎉 The convergence of AI and healthcare is gaining momentum, and we’re excited to contribute to this dialogue. Key highlights: - The “Big Data in Oncology” track showcased diverse perspectives on data extraction, structuring, and clinical applications. Our CEO, Thomas Hufener, presented on “AI-Powered Multimodal Clinical Intelligence: The Next Frontier in Precision Oncology,” emphasizing the need for clinical collaboration. - Despite the AI buzz, many companies still focus on traditional machine learning, with foundation models in healthcare just starting to gain traction. AI's ability to integrate genomic data with clinical data (imaging, pathology, and patient records) is crucial for enhancing cancer care decisions. - Clinical collaboration remains vital, yet many AI initiatives prioritize upstream applications (e.g., drug discovery) due to hospital complexities. - Emerging trends include: - Real-time treatment monitoring using multimodal data - Enhanced diagnostics through AI-augmented imaging and genomics - A shift towards preventive care and risk prediction - Growing recognition of the gap between AI's potential and its current implementation in clinical settings. We’d like to especially acknowledge the professionals we were fortunate to connect with and learn from, including Philipp Pauli, Christophe Dufour, Georgia Chan, Jean-Pierre Hubaux, Jacob Reimers, Jon Teague, Shayoni Dutta, Mieke Van Hemelrijck, Mike Rossi, Karl Smith Byrne, and Carian Boorsma, PhD. A big thank you to everyone we connected with at BioTechX—your insights have inspired and energized us for the possibilities ahead! #BioTechX #AIinHealthcare #AIOncology
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We are proud to announce that Unilabs, one of the largest diagnostic providers in Europe, is harnessing SOPHiA GENETICS’ AI technology across its network in Switzerland to enhance testing for HRD-status in solid tumors. “SOPHiA GENETICS’ AI-based technology is at the forefront of where precision medicine is going – blending science and technology to deliver the best possible outcomes for patients. The addition of the SOPHiA GENETICS Platform to our suite of offerings will support our effort to deliver the fastest and most accurate diagnostics to our patients,” said Mattia Schmid, PhD., FAMH, Scientific Manager, Unilabs. HRD, a key predictor of tumor response to certain treatments, requires detailed analysis to detect. Our platform uses AI and machine learning to efficiently interpret complex NGS data, providing reliable HRD results that are essential for effective treatment planning. Kevin Puylaert, Managing Director, EMEA at SOPHiA GENETICS, noted, "As a diagnostics leader, Unilabs is responsible for delivering fast and accurate testing results to patients throughout Europe each year, and our team at SOPHiA GENETICS is proud to be one of the technology leaders helping to enable these results." Learn more: https://loom.ly/xJ9AB7o #HRD #DataDrivenMedicine #AIinHealthcare #AIforGood
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🌟 Unlocking the Future of Precision Oncology: Key Insights from Industry Leaders 🌟 In the ever-evolving landscape of precision oncology, our experts are leveraging advanced technologies like AI, ML, robotics, and multi-omics tools to drive targeted treatments. Despite ongoing challenges in managing high-quality biomaterials and clinical data, significant growth opportunities have been identified to propel the industry forward. 🚀🌱 🔗 Missed our recent Think Tank on 'Strategic Positioning in Precision Health: Industry Players and Competitive Benchmarking in Precision Oncology'? 🖥️ Watch the recorded session of the Think Tank https://frost.ly/9ws 🌱 Read full article here https://frost.ly/a1p #PrecisionOncology #Biomarkers #HealthcareTransformation #FrostSullivan #PrecisionHealth Nathan Fowler, MD BostonGene
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🔬 At Pierre Fabre, we're harnessing the power of Artificial Intelligence (AI) to transform the #Oncology care pathway 🧬: from prevention and diagnosis to treatment and support. Our mission for the upcoming years is to democratize custom-tailored healthcare, making it accessible to all on a global scale. 🌍 🤖 With AI's augmented capabilities, we're poised to incorporate a vast array of physiological and environmental factors, directly impacting patient health outcomes. This innovation paves the way for us to foresee disease progression and provide targeted care. 🎯 🚀 The surge in computing power is propelling us toward groundbreaking discoveries, revealing rare genetic mutations and molecular irregularities linked to various cancers. 🧩 By merging cancer genetics, extensive population datasets, and #AI, we're at the forefront of a revolution in precision oncology. 🌟 Deep learning algorithms are now key players in pinpointing novel therapeutic targets and refining personalized treatment strategies. 💡 In collaboration with our biotech partners, we're on a quest to discover the next generation of oncology drugs, crafting precision medicine that caters to the unique needs of each patient. 🤝 👉 Learn more on Pierre Fabre Oncology #PrecisionMedicine #ArtificialIntelligence #HealthcareInnovation Pierre Fabre Group
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🌟 AI in Predictive Biomarker Patient Matching: Revolutionizing Personalized Medicine 🌟 The shift towards personalized medicine is reshaping cancer care, offering tailored treatments that improve outcomes and minimize exposure to ineffective therapies. Biomarkers—key molecules indicating biological states—are at the forefront of this revolution. When used effectively, they can significantly boost treatment success rates. However, challenges like data integration, the dynamic nature of biology, and disease heterogeneity have hindered progress. Enter AI. By leveraging machine learning, AI can analyze complex data, track dynamic biomarkers, and predict patient responses, ultimately guiding clinicians toward the most effective treatments. This AI integration promises enhanced patient outcomes, greater clinical trial success, and reduced healthcare costs. At LifeTech Staffing, we're excited to support the growth of AI-driven solutions in precision medicine, connecting top talent with opportunities to make a real impact. Read the full article at https://rb.gy/yxkcin #PersonalizedMedicine #ArtificialIntelligence #Biomarkers #PrecisionMedicine #LifeTechStaffing #HealthcareInnovation
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We would like to introduce #CHIRONProject's another partner e-NIOS, the first Greek Digital Biotech SME, which is a spinoff company of the National Hellenic Research Foundation. Having its premises in the municipality of Kallithea, in the broader Athens area, e-NIOS is a deep tech company, active in the field of automated, unsupervised interpretation of Biomedical Big Data leveraging powerful, agile, AI techniques for efficient Multi-Omic data integration and semantic analysis. An important milestone for e-NIOS was its 1st winning position in the 1st Start4Health Digital Health Program 2022 of the Center for Digital Innovation (CDI) of Pfizer, which opened the way for a productive partnership with Pfizer CDI in order to develop an innovative solution that overcome current analytic barriers and limitations to aid biomarker and early drug discovery. CHIRON’s main goal is to develop novel therapies to make tumour cells sensitive again towards cell death via a particular death pathway (TRAIL/DR). e-NIOS contributes to these efforts with its internationally pioneering expertise and analytical solutions in unsupervised, data-driven, Biomedical Big Data Interpretation. e-NIOS develops and offers a unique framework that breaks the interpretation bottleneck regarding complex genomic data, providing statistically rigorous, data-driven pipelines for streamlined biomarker discovery, robust patient stratification and novel drug discovery/repurposing. Its pioneering analytic core implements AI techniques in the biomedical semantics data space, establishing a robust framework for unsupervised, intelligent Semantic Network Analysis. This enables agnostic, dynamic prioritization of critical cellular pathways and more importantly distinct, nodal, linker genes (regulatory hubs) in diverse disease contexts. In the CHIRON project, e-NIOS will join forces with Anyo Labs to develop solutions that aid the chemoinformatics analytic pipelines through omics-driven prioritization of important protein interactions for the phenotype under investigation. On another aspect, e-NIOS will supervise the task of the interpretation of the streams of omics experiments that will be run by several CHIRON partner groups to elucidate the architecture and dynamics of TRAIL/DR-pathway in different cellular contexts (innate-like T cells like NKT cells, MAIT cells, and gd T cells, macrophages, NK cells, TRAIL non-canonical signaling in cancer cells). Dimitris Zisis Aristotelis Chatziioannou Eleftherios Pilalis Christina Andrinopoulou #TRAILsignalling #BioInfoMiner #Datadriven #InterpretationofbiologicalBigData
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The Curious Case of Molecular Diagnostics: A Journey Through Innovation 🧬 Imagine a bustling hospital room in the near future. A patient arrives with flu-like symptoms that could be anything from a seasonal virus to a rare genetic disorder. Traditionally, diagnosing this case could take days—sometimes weeks. But not today. The doctor walks in with a sleek, handheld device resembling a high-tech scanner. “Let’s run a quick test,” she says. Within minutes, the device flashes a result: not just the pathogen responsible, but also insights into the patient’s genetic predispositions and suggested personalized treatments. This isn’t science fiction—it’s the reality that molecular diagnostics is shaping, thanks to groundbreaking advancements: 1️⃣ CRISPR-based Diagnostics: Imagine this technology as a pair of molecular scissors, cutting through complexity to pinpoint pathogens and mutations with unparalleled accuracy. What used to take laboratories hours now happens in moments. 2️⃣ Point-of-Care Testing: Picture these tests in remote villages or crowded urban clinics, delivering real-time results without the need for large labs. They’re revolutionizing access to healthcare. 3️⃣ Next-Generation Sequencing (NGS): It’s like taking a deep dive into a genomic ocean, exploring every single gene with precision and scale never thought possible. This technology uncovers mysteries of rare diseases and redefines cancer treatments. 4️⃣ AI-Powered Insights: Imagine a digital Sherlock Holmes, using AI to analyze mountains of data, identify trends, and suggest treatments tailored to each individual. 5️⃣ Digital PCR: Think of this as a molecular detective, quantifying DNA and RNA with such precision that even the smallest details can’t escape its detection. These innovations are more than technological marvels—they’re lifelines. They enable earlier disease detection, effective treatment strategies, and equitable access to healthcare, even in underserved regions. As we journey through this revolution, it’s clear that collaboration across industries and disciplines will amplify the impact of these advancements. Together, we’re not just envisioning the future of healthcare—we’re building it. 🌟 What part of this story excites you the most? Let’s discuss how we can be part of this transformative journey! #ZyGene #Biotechnology #MolecularDiagnostics #HealthcareInnovation #PrecisionMedicine #CRISPR #NGS #AIInHealthcare #Diagnostics
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What would you say is the ratio of breakthroughs to breakdowns in AI drug development? ⚖️ Yesterday at BioTechX Europe, our CTO, Miha Stajdohar, tackled this question in a panel. Thank you, Blanca Baez (DBounce Ltd), James Zanewicz, JD, LLM, RTTP (Tulane University School of Medicine), Bruce Press (ZS), and Martin Akerman (Envisagenics) for a lively discussion! In case you missed it, you still have a chance to catch Miha in action today. 💡"Foundation Models for RNA Biomarkers" 🕛 12:45 PM 📍 Theatre 3 - AI in Drug Development and Discovery Hope to see you there! #BioTechX The Alliance for Artificial Intelligence in Healthcare (AAIH)
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It’s been incredible to watch researchers dive into TrialsSphere, finding everything from GLP1 therapies to granulosa cell tumor trials in a fraction of the time it used to take. 🔥🔥🔥 Seeing how efficiently they’re discovering the most relevant trials and drafting new protocols with GenAI has been amazing. 🤩 What once felt like a long, tedious process is now streamlined and intuitive—and the best part? It’s free to use. 🚀🚀🚀 We’re excited to see how TrialsSphere is already transforming research, and we can’t wait to bring even more features to life. 👍 The future of clinical trials is here—and it’s just getting started. #ClinicalTrials #GenAI #HealthcareInnovation #TrialsSphere #ResearchRevolution #Efficiency #AI #research #researchers #clinicaltrial
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This is tremendously exciting! The largest #OpenSource initiative in #ComputationalPathology by far. It includes the #Virchow #FoundationModel, trained on billions of images from 1.5 million slides, available under the Apache 2.0 license for everyone to use. On top of that, the #PRISM model, which provides whole-slide embeddings for pan-cancer detection, subtyping, and IHC biomarker prediction. Download them and try them out! It takes an entire field to revolutionize cancer research and make a tangible clinical impact on patient care.
Our open-source initiative, Open Paige Foundation Model (Open PFM) provides access to our best-in-class technology and underscores our commitment to driving innovation, collaboration, and accessibility in AI research. 𝗖𝘂𝗿𝗿𝗲𝗻𝘁 𝗺𝗼𝗱𝗲𝗹𝘀 𝗮𝘃𝗮𝗶𝗹𝗮𝗯𝗹𝗲 𝗼𝗻 𝗢𝗽𝗲𝗻 𝗣𝗙𝗠: 𝗩𝗶𝗿𝗰𝗵𝗼𝘄: • 1.5 million WSI, 600 million parameters • State-of-the-art performance published in Nature Medicine • Pan-cancer and rare cancer detection • Tile Embeddings & fine-tuning capabilities • Available under the Apache 2.0 License 𝗩𝗶𝗿𝗰𝗵𝗼𝘄 𝗣𝗲𝗿𝗳𝗼𝗿𝗺𝗮𝗻𝗰𝗲: https://lnkd.in/gSDiJisg 𝗠𝗼𝗱𝗲𝗹 𝗔𝗰𝗰𝗲𝘀𝘀: https://lnkd.in/eMFmpRpS 𝗣𝗥𝗜𝗦𝗠: • Built using Virchow • 587,000 additional WSI, and 195,000 clinical reports • Pan-cancer detection, subtyping and IHC biomarkers prediction • Slide Embeddings & fine-tuning • Available under the CC-BY-NC-ND 4.0 License 𝗣𝗥𝗜𝗦𝗠 𝗣𝗲𝗿𝗳𝗼𝗿𝗺𝗮𝗻𝗰𝗲: https://lnkd.in/e482uPMP 𝗠𝗼𝗱𝗲𝗹 𝗔𝗰𝗰𝗲𝘀𝘀: https://lnkd.in/e27vM59V 𝗚𝗶𝘁𝗛𝘂𝗯: https://lnkd.in/e5JQqEQe All available models of Open PFM can be accessed on Hugging Face: https://lnkd.in/e_RemKce
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#PRECISIONMEDICINE #PATHOLOGY, #BIOMARKER DEVELOPMENT, or related fields know that #digitalpathology is the single-most promising technological advancement that will revolutionize medicine forever. Learn more: https://ter.li/0cs7wx
Anyone who is working in precision medicine, pathology, biomarker development, or related fields know that #digitalpathology is the single-most promising technological advancement that will revolutionize medicine forever. Yet, to date, not one #industrydedicated meeting has united all leading biopharma to tackle the current bottlenecks preventing this field from taking off. Enter the 'Translational Digital Pathology & AI Summit' - whether you are new to the space, or looking to refine your expertise, this summit is uniting all stakeholders to overcome regulatory hurdles, foster collaborations, and accelerate the adoption of digital pathology and AI in translational research and clinical practice. The last early bird for this summit closes this Friday (15th March). Make sure you complete your registration today to save over $400! You can use this link to find out more: https://ter.li/0cs7wx Erik Hagendorn, Sabya Biswas, Mark Gustavson, Jessica Baumann, MD, FCAP, Jimmy Tran, Meijian Guan, Lauri Diehl, Claudia Dollins, Edwin Roger Parra Cuentas, Chris Garcia, Jennifer Quigley, Sarah Vargas, Iman Tavassoly MD, PhD, Heike Fuhrmann-Stroissnigg, Zoltan Laszik, Lucy Phillips
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