Prashant Desai’s Post

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Helping You Stay Fit and Healthy | Stanford School of Medicine | Longevity Biohacker | Published Author | IG: 1M+ followers

‼️Wake up India: Epigamia co-founder Rohan Mirchandani, 42, died from a sudden cardiac arrest. 1 in 4 reading this in India will die of a disease of the heart (Atherosclerosis). 33% of these will experience their first cardiac event as ‘sudden death’ like Rohan Mirchandani or Ambareesh Murthy of Pepper Fry☹️ 🧐Is Atherosclerosis really sudden? I lost my father (at 37) & my brother (35) to heart disease (not an attack). I am at high risk of the same. Thus, I have read a lot on heart attack ➕ stroke. Here are some things every Indian must know: 1️⃣ It is the no.1 killer in India & the world 2️⃣ Atherosclerosis is ubiquitous & inevitable. You either die from or with it 3️⃣It starts in your teens (7% deaths) but takes decades to manifest 4️⃣Women are 10x more at risk to die from Atherosclerosis than breast cancer 5️⃣The medical world knows a lot about Atherosclerosis. We can delay it 6️⃣Your biggest risk🟰AGE 7️⃣We blame cholesterol but there is no such thing as good or bad cholesterol. No cholesterol🟰No life. Not more than 10% of dietary cholesterol makes its way into circulation Then what causes it?🤨 Body makes its own cholesterol, some cells more & some less. Hence needs transportation to the ones that make less. It is the transportation of cholesterol and triglyceride inside a lipoprotein (both being hydrophobic) that starts the process of Atherosclerosis. Every Lipoprotein vehicle that transports is wrapped with apoB. The number of vehicles🟰Lipoprotein/apoB is a predictor of risk. Sadly we measure weight as a risk. Wrong. The NMR technology that can detect apoB particles or LDL particles that predict the risk decades early is not available in India. While travelling inside the blood vessel, apoB particles get stuck in the single layer endothelial and release oxidative stress. Body sends soldiers to fight➕repair the damage. The more damage (smoking/blood pressure/carbs/sugars etc) the more repair is needed. As the damage continues the repair process accelerates breaks open, and enters the blood vessel and body sends bigger tanks and aircraft to combat resulting in plaque, narrowing the blood vessel and restricts the flow of oxygen leading to heart attack or stroke💔 You can also see the blockage through the latest tech like CT scans🩻 What can you do? 1 Tests regularly. If you travel abroad, test for apoB/LDL-P 2 If not, use LDL-C as a proxy. If high, bring it down. Speak to your cardiologist. Use medication like Statins or CPSK9 inhibitors.  3 After age, big contributors🟰smoking & blood pressure. 4 Exercise is the biggest weapon for heart health.  5 Sleep for 8 hours. Under sleep even for 2 hours increases your risk of heart attack by 200% 6 Eat less. Law of thermodynamics. All excess energy will be converted into fat (triglycerides). The more triglyceride, the more vehicles required. Take charge NOW! I know most likely I will die from it but I am doing everything I can to delay it + give it a tough fight💪 #heart #health

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Dr Ashwani Garg

Functional Medicine I Chronic Disease Reversal & Brain Health Consultant I Mitochondrial Augmentation | Peptides | Regenerative Medicine

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Adding additional points 1. Get lots of sunlight: improves Nitric oxide thus dilate blood vessels 2. Avoid man made (non native EMF): impacts metabolism negatively thus reducing smooth muscle function in blood vessels and causes artery brittling 3. Reduce inflammatory omega 6 fatty acids from refined and seed oils 4. hydrate yourself with good quality structured water with Celtic salt. (Lack of trace minerals can cause calcification) 5. Reduce inflammatory foods: reducing inflammation will help blood vessels maintain lumen 6. Keep your digestive healthy: unhealthy digestive system releases endotoxins thus systemic inflammation and bad impacts on cardiovascular system Bottom line: it’s a metabolic disorder: means mitochondria is impacted. Keep mitochondria healthy to keep your cardiovascular system healthy

CA. Umesh Bhalerao

Asset Management | Hedge Fund and Private Equity financial reporting | Ex-big4

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Thanks for sharing this Prashant Desai. Can you please elaborate little more on eat less.

Dear Prashant Desai sir! More than half of what I see in this post appears to be from the book Outlive. Credits missing?

Uzma Hameed

Associate Director @ Elanco - Omnichannel Marketing| MarTec| Digital | Customer Experience

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What should be ideal LDL-C target?

You could simplified the explanation a lot more with a diagram or visual

Elamurugan N

ex-Singapore Airlines || Thought Leader || Speaker || Change Maker || Investor || Entrepreneur || Mental Health || Bullish on Bharat

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A human being is born to die Prashant Desai All it requires between this period is - a home to live - food for the living - a decent clothes to wear. Beyond this everything is luxury and the luxury varies from person to person. Wondering if this could be because of Covid OR Vaccine 🤔 My suggestion at 63 is: ↳ A yearly once or twice complete medical check up is a must. ↳ I don't drink. ↳ I don't smoke. ↳ I am not obese ( see the picture below) ↳ I don't have diabetes ↳ BP is around 130/70 ↳ I was a long distance runner. ↳ I am a pure vegetarian ↳ I go for one hour of walking even now. ↳ I went up to Nationals in Karate in 1982 ↳ I practice yoga now ↳ I sleep 8-9 hrs a day ↳ I have never taken any medicine until 61. This June 2023 went for a walk and while coming closer to my house lost consciousness and rushed to hospital & finally had to under go an OPEN HEART surgery. I got retired in April 2021 and now 63 yrs young. I am perfectly fine now. But, none of my friends and relatives believed when I said this knowing about me. Don't take life and things for granted. We need more 𝐛𝐥𝐞𝐬𝐬𝐢𝐧𝐠𝐬 in our account than 𝐌𝐨𝐧𝐞𝐲. Just Stay Humble. Love everyone. Be Kind.

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Basant T.

"It's easier to invent the future than to predict it." Connect, Communicate and Collaborate Better with BTBIZ Group.

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1. Get CT Coronary Angio and Liver scan (USG abdomen /fibroscan)each year once you turn 25. That early. It’s 3-4 minutes scan each. 2. sleep well not more. 7 hours will do where deep and rem are 90 minutes each. 3. Zone 2 cardio 4. Lift some weights/do resistance training 5. Eat whole food, fruits, veggies ,legumes 6. Ensure oral and gut health is good. 7. Never take statins for cholesterol . 8. Vit D, Magnesium,Zinc, Omega 3 are must.9.Must get sunlight and social activity daily

Voice Of Health Dr Parthiban Marimuthu

Director | Inflammation Control, Grannyceuticals@, Therapeutic Food Ingredients, Patient Care, Strategy

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Behave like natural human. Don't think that after education educated urban humans are made robot. Don't think you have mediclaim policy. Disease is not part of healthy life style. Sudden haemorrhage in brain, heart attack, stroke are outcome of ruthless irresponsible life style. No farm labour or soldier come across mysterious deaths like educated urban humans who are largely science abused. Tradition lost population is a displaced society in refugee camps

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Anil Inani

CFO and Business Commercial Operation Leadership Role. Skilled at Achieving Higher EBITDA and P&L Responsibilities.

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The effectiveness of statins in reducing LDL cholesterol is often temporary, as levels tend to rebound to their original state once treatment is stopped. Moreover, long-term statin use can have adverse side effects. A friend of mine successfully reversed his diabetes within 2 years, discontinued metformin, and now maintains an HbA1c level of 5.5. Despite adopting a healthier lifestyle, including weight loss and a balanced diet, he has been unable to lower his LDL cholesterol levels.

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