Cue Health’s Post

A study co-authored by #URochesterResearch professor Elaine L. Hill shows that the severity of #COVID reinfection is linked to the severity of initial infection. The study, which investigated N3C data from 3 million patients, also showed that #LongCovid is more likely after initial infection than reinfection. Read the full study in Nature Portfolio's Communications Medicine >> https://lnkd.in/euTQNPeq University of Rochester researchers who would like to access secure COVID patient data can join the N3C Data Enclave >> https://lnkd.in/e3W_QNxA

“Addressing the problem of Long-COVID is not only a moral imperative - it’s also an economic imperative.” Dr. Ziyad Al-Aly MD On January 18, 2024 Dr. Ziyad Al-Aly testified to the growing problem of Long-COVID before the US Senate. In February I was able to interview Dr. Al-Aly myself. Over 65 Million people worldwide are suffering from Long-COVID & that number increases every hour, with every infection. March 15 was Long Covid Awareness Day. Please join me in raising awareness in our exclusive interview with Dr. Ziyad Al-Aly on the science of Long-COVID and the problems with recurrent SARS-CoV-2 infection. Now posted on the Friendly Pharmacy 5 Channel. (If nothing else, enjoy this 🔥 intro by my editor and producer below) CHAPTERS: 00:00 Dr. Ziyad Al-Aly's story 04:40 Proton Pump Inhibitors and Dr. Al-Aly’s research 06:48 Understanding Long-COVID in 2020 13:06 PLRC: Patient Driven advocacy for Long-COVID 14:33 Numbers associated with Long-COVID 20:45 Post-acute Sequelae across multiple organ systems 25:15 Risk of Long-Covid with each infection 27:20 Hybrid Immunity Fallacy 30:45 Kidney Decline with COVID-19 infection 33:39 Brain and Cognitive Decline and COVID-19 36:35 Viral Persistence, Gut Health and COVID-19 43:42 Paxlovid and Long-COVID 45:38 Economic Impact of COVID-19 infection 50:28 Ventilation and other prevention methods for COVID-19 #LongCovidAwarenessDay #LongCovid #patientadvocacy #longcovidresearch

A recent study from Dysautonomia International Medical Advisory Board member Dr. Blair Grubb found that COVID-19 infection in people with pre-existing #POTS often leads to worsening of POTS symptoms, including syncope, palpitations and tachycardia, orthostatic dizziness, and fatigue. A total of 41 POTS patients with confirmed COVID-19 infection were included in the study. 93% reported having worsening of their baseline POTS symptoms during the acute infection, 68% experienced worsening of their dysautonomia symptoms for at least 1-6 months post-infection; and 73% required additional medications to manage their symptoms. Medications such as ivabradine, fludrocortisone, midodrine and pyridostigmine resulted in partial improvement in orthostatic intolerance symptoms for a majority of the patients that were treated. The researchers noted possible mechanisms by which COVID can cause autonomic dysfunction, including the virus causing hypovolemia, infecting postganglionic sympathetic nervous system neurons, or invading the brainstem and medullary system. Read the study abstract: https://lnkd.in/eh7wvvky Dysautonomia International is funding POTS, dysautonomia and Long COVID research at Dr. Grubb’s lab and other medical centers. You can help support this research by making a contribution at https://lnkd.in/gDAYbeEi.

Effectiveness and impact of universal prophylaxis with nirsevimab in infants against hospitalisation for respiratory syncytial virus in Galicia, Spain. Nirsevimab substantially reduced infant hospitalisations for RSV-associated LRTI, severe RSV-associated LRTI requiring oxygen, and all-cause LRTI when given in real-world conditions. These findings offer policy makers and health authorities robust, real-world, population-based evidence to guide the development of strategies for RSV prevention. https://lnkd.in/dcxWG3Rx

ASCP Daily Diagnosis 06/21 CST Recommendations regarding the use of respiratory isolation and restrictions for patients with pulmonary tuberculosis in community settings were developed to ensure a balance between public health benefits and potential patient harms. Additional research is needed to quantify the proportion of TB transmission that is avertable by community-based respiratory isolation and restrictions, acknowledging that the majority of transmission may occur prior to diagnosis and any respiratory isolation and restrictions interventions. https://lnkd.in/gFG3MxZ7

📃Scientific paper: A Bayesian Survival Analysis on Long COVID and non Long COVID patients: A Cohort Study Using National COVID Cohort Collaborative (N3C) Data Abstract: Since the outbreak of COVID-19 pandemic in 2020, numerous researches and studies have focused on the long-term effects of COVID infection. The Centers for Disease Control (CDC) implemented an additional code into the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) for reporting ‘Post COVID-19 condition, unspecified (U09.9)’ effective on October 1st 2021, representing that Long COVID is a real illness with potential chronic conditions. The National COVID Cohort Collaborative (N3C) provides researchers with abundant electronic health records (EHR) data by aggregating and harmonizing EHR data across different clinical organizations in the United States, making it convenient to build up a survival analysis on Long COVID patients and non Long COVID patients among large amounts of COVID positive patients. Continued on ES/IODE ➡️ https://etcse.fr/ehc ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

📃Scientific paper: A Bayesian Survival Analysis on Long COVID and non Long COVID patients: A Cohort Study Using National COVID Cohort Collaborative (N3C) Data Abstract: Since the outbreak of COVID-19 pandemic in 2020, numerous researches and studies have focused on the long-term effects of COVID infection. The Centers for Disease Control (CDC) implemented an additional code into the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) for reporting ‘Post COVID-19 condition, unspecified (U09.9)’ effective on October 1st 2021, representing that Long COVID is a real illness with potential chronic conditions. The National COVID Cohort Collaborative (N3C) provides researchers with abundant electronic health records (EHR) data by aggregating and harmonizing EHR data across different clinical organizations in the United States, making it convenient to build up a survival analysis on Long COVID patients and non Long COVID patients among large amounts of COVID positive patients. Continued on ES/IODE ➡️ https://etcse.fr/ehc ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

📃Scientific paper: A Bayesian Survival Analysis on Long COVID and non Long COVID patients: A Cohort Study Using National COVID Cohort Collaborative (N3C) Data Abstract: Since the outbreak of COVID-19 pandemic in 2020, numerous researches and studies have focused on the long-term effects of COVID infection. The Centers for Disease Control (CDC) implemented an additional code into the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) for reporting ‘Post COVID-19 condition, unspecified (U09.9)’ effective on October 1st 2021, representing that Long COVID is a real illness with potential chronic conditions. The National COVID Cohort Collaborative (N3C) provides researchers with abundant electronic health records (EHR) data by aggregating and harmonizing EHR data across different clinical organizations in the United States, making it convenient to build up a survival analysis on Long COVID patients and non Long COVID patients among large amounts of COVID positive patients. Continued on ES/IODE ➡️ https://etcse.fr/ehc ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

📃Scientific paper: A Bayesian Survival Analysis on Long COVID and non Long COVID patients: A Cohort Study Using National COVID Cohort Collaborative (N3C) Data Abstract: Since the outbreak of COVID-19 pandemic in 2020, numerous researches and studies have focused on the long-term effects of COVID infection. The Centers for Disease Control (CDC) implemented an additional code into the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) for reporting ‘Post COVID-19 condition, unspecified (U09.9)’ effective on October 1st 2021, representing that Long COVID is a real illness with potential chronic conditions. The National COVID Cohort Collaborative (N3C) provides researchers with abundant electronic health records (EHR) data by aggregating and harmonizing EHR data across different clinical organizations in the United States, making it convenient to build up a survival analysis on Long COVID patients and non Long COVID patients among large amounts of COVID positive patients. Continued on ES/IODE ➡️ https://etcse.fr/ehc ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.

This study investigated the risk factors and outcomes in elderly patients with community-acquired carbapenem-resistant K. Pneumonia (CRKP) infections. Recent intensive care unit (ICU) admission and prior carbapenem use are independent risk factors for CRKP infection in elderly patients. Compared to patients with carbapenem-sensitive K. pneumoniae infection, those with CRKP infection had a significantly higher risk of adverse outcomes, including ICU care, respiratory failure, septic shock, and 90-day mortality. https://lnkd.in/ejpJujs8