BioMedHack’s Post

Neurological diseases now surpass cardiovascular diseases as the leading cause of global morbidity and disability, affecting over 3 billion people worldwide. A study published in Lancet Neurology reveals a 20% rise in neurological conditions over the last two decades, with stroke, dementia, diabetic neuropathy, and autism among the most prevalent. However, prevention strategies, such as vaccines and reducing risk factors like high blood pressure and smoking, offer hope. Prioritizing brain health through public education, campaigns, and accessible guidelines is essential to combat this growing crisis and improve global health outcomes. If you are interested in reading more on the topic please read my recent blog: https://bit.ly/3Zt401y 🌐 www.drdomenicopratico.com | www.thepraticolab.com 📚 https://lnkd.in/ePYMYRWn 🧠 https://lnkd.in/eJjn_Shz 🐦 https://lnkd.in/e-NvsgBK 🖋️ https://lnkd.in/ecVzXE8D #NeurologicalHealth #BrainHealth #GlobalHealth #StrokePrevention #DementiaAwareness #AutismAwareness #DiabeticNeuropathy #PublicHealth #HealthEducation #PreventiveCare #HealthCampaigns #MedicalResearch #MorbidityReduction #HealthEquity #LancetNeurology #praticolab #alzheimersresearch #alzheimerscare #alzheimersawareness #domenicopratico

Exited to share my latest Book chapter✨, where we discussed the application of nanoparticles to address the blood brain barrier penetration for the treatment of various neurological diseases. https://lnkd.in/g7Hrh9Uw #Nanoparticles, #DrugDilevery, #CentralNervousSystem Disorders, #BloodBrainBarrierPenetration, #NeurologicalDiseasemanagement

MENTAL STOP 44: RARE DISEASES These rare sicknesses weave a complex tapestry of symptoms, challenging both patients and healthcare professionals in their quest for understanding. Imagine navigating the labyrinth of a disease that not only affects your neurons but eludes a clear diagnosis. These rare neuronal afflictions cast a shadow on the lives of those grappling with mysterious symptoms, as they confront the uncertainty of an illness without a name. The journey begins with subtle signs, perhaps a slight tremor or intermittent cognitive lapses. As time progresses, these symptoms intensify, manifesting into a labyrinth of neurological challenges. The lack of a prompt and accurate diagnosis adds another layer of complexity, leaving patients in a state of limbo, grasping for answers in a medical puzzle. For those who endure the burden of these rare sicknesses, the impact is profound. The conditions exacerbate over time, morphing into chronic challenges that significantly alter the course of daily life. Simple tasks become arduous, and the unpredictability of symptoms casts a perpetual shadow on one's well-being. Early and precise diagnosis is not only crucial for developing effective treatment strategies but also for providing much-needed clarity and support to those on the frontline of this silent battle. #RareNeuroChallenges #EnigmaticIllness #NeuroMystery #UnravelingNeurology #RareDiseaseAwareness #ChronicNeuroStruggle #MedicalEnigma #NeuroCommunity #InvisibleIllnessJourney #SeekingDiagnosis

Neurological diseases now surpass cardiovascular diseases as the leading cause of global morbidity and disability, affecting over 3 billion people worldwide. A study published in Lancet Neurology reveals a 20% rise in neurological conditions over the last two decades, with stroke, dementia, diabetic neuropathy, and autism among the most prevalent. However, prevention strategies, such as vaccines and reducing risk factors like high blood pressure and smoking, offer hope. Prioritizing brain health through public education, campaigns, and accessible guidelines is essential to combat this growing crisis and improve global health outcomes. If you are interested in reading more on the topic please read my recent blog: https://bit.ly/3Zt401y 🌐 www.drdomenicopratico.com | www.thepraticolab.com 📚 https://lnkd.in/ePYMYRWn 🧠 https://lnkd.in/eJjn_Shz 🐦 https://lnkd.in/e-NvsgBK 🖋️ https://lnkd.in/ecVzXE8D #NeurologicalHealth #BrainHealth #GlobalHealth #StrokePrevention #DementiaAwareness #AutismAwareness #DiabeticNeuropathy #PublicHealth #HealthEducation #PreventiveCare #HealthCampaigns #MedicalResearch #MorbidityReduction #HealthEquity #LancetNeurology #praticolab #alzheimersresearch #alzheimerscare #alzheimersawareness #domenicopratico

“Long COVID” may be due to low circulating levels of serotonin, thereby impacting how the nervous system functions. “Long COVID” refers to long-term effects from infection by the COVID virus. Long COVID can affect nearly every organ system, and patients can present with a host of symptoms. In terms of neuropsychiatric symptoms, patients commonly report intense fatigue, brain fog, lack of motivation, and difficulty with memory. Long COVID continues to be a mysterious illness, but researchers may have a possible explanation for why long COVID develops. In a study published in Cell, researchers discovered that patients with long COVID exhibited lower circulating levels of serotonin. They presented several reasons for the low serotonin, including decreased absorption via the intestinal lining. Decreased serotonin impacted the vagus nerve’s proper functioning long term, which in turn led to problems with memory. Learn more by reading our blog post, Reduced Serotonin Levels Linked to Long COVID: https://buff.ly/49CLLJj #CalPsychiatry #latherapy #SerotoninLevels #longcovid

#New_Publication_2024 #The_Lancet_Neurology 📣 Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021. 🔺https://lnkd.in/dvCA2WGQ #Nervous_system #Systematic_analysis #Global_Burden_Disease #CNS

Did you know that #neurological disorders are now the leading cause of disability worldwide? While #MentalHealth conditions contribute nearly 5% to the global disease burden. Our October newsletter explores the disease burden and highlights the large #TreatmentGap for these conditions, especially in low-income countries where up to 96% of affected individuals go untreated. Could neuroplasticity-promoting therapies, like #neuroplastogens, offer new hope for treating depression and neurodegenerative diseases? 🧠 Our newsletter also features research highlights, including: - Antidepressant discontinuation and psilocybin efficacy - Psilocybin-assisted neurofeedback treatment - Study design and its impact on psychedelic efficacy outcomes - Psychedelics in autistic adults - BDNF as a predictor of antidepressant response - The role of serotonin receptors in disease mechanisms 🥼 Plus, new clinical trials exploring psilocybin for ALS and cognitive control in seizure disorders, and the use of THC as an active placebo! 👉👉Explore these topics and more in our latest newsletter: https://lnkd.in/gEe-fJ8i Subscribe today to stay on the cutting edge of neuroscience research and clinical advancements.

Parkinson’s disease is a progressive neurological disorder marked by symptoms such as tremors, rigidity in the limbs, issues with balance, and psychological impacts like anxiety and depression. Approximately 90,000 individuals are newly diagnosed with this condition annually, and it is estimated that up to 10 million people are currently living with it around the globe. While the exact cause remains unknown, emerging research indicates that Parkinson’s disease may originate in the gut and subsequently spread to the brain. #ParkinsonsDisease #Neurology #HealthAwareness #MedicalResearch #MentalHealth #GutBrainConnection #ChronicIllness #HealthUpdates

Fascinating insights into the intricate relationship between the gut and brain. This article sheds light on how our gut might play a pivotal role in neurodegenerative disorders like Parkinson’s. The idea that something as routine as a colonoscopy could one day offer early warnings about brain health is both exciting and hopeful. This research underscores the importance of exploring the gut-brain connection further—who would’ve thought the 'second brain' in our gut holds so many answers to diseases we’ve long struggled to understand? A long read though.

Doppel (PRND): A Game-Changer for Brain Health Introducing doppel (PRND), a protein similar to the infamous prion protein but with a very different role. Recent research reveals that PRND plays a crucial part in neuron survival and protection, helping to shield the brain from oxidative stress and harmful factors. 🧠 Unlike its counterpart that causes deadly prion diseases, PRND offers exciting therapeutic potential. Medications that enhance PRND function could help combat conditions like Alzheimer’s and ALS, potentially slowing or even halting nerve cell degeneration. 🌟 Scientists are eager to understand how PRND works and its potential applications in brain health. The future of treatments for neurodegenerative diseases could rest on unlocking the secrets of this fascinating protein! 💉 https://lnkd.in/eCeEXXXG #PRND #BrainHealth #NeurodegenerativeDiseases #Alzheimers #ALS #MedicalResearch #ProteinTherapies