At Ansa, we’re on a mission to end the headaches of ordering synthetic DNA and give researchers what they really want: reliable DNA, on time, exactly as ordered. With the exciting launch of our 5 kb clonal product today, our co-founder and Director of DNA Assembly, Jared Ellefson, shares how this will impact the scientific community. Read the blog: https://lnkd.in/ghMVuaEC
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Our work on Evo was just published! Evo is a genomic foundation model that can read DNA's universal language to understand not just DNA itself, but also the proteins and RNAs it encodes. We've demonstrated this multimodal understanding by using Evo to generate novel functional CRISPR-Cas and transposon systems - marking the first time a language model has successfully codesigned both protein-RNA and protein-DNA complexes! https://lnkd.in/gV3X_3EZ
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This is amazing! Language models have already done amazing things in protein engineering, but Evo takes it to a whole new level. Multimodal integration between DNA, RNA and Proteins can contribute so much more to Synthetic Biology as well as understanding evolution. It’s exciting to see how AI is unlocking the secrets of biology and helping us design life in ways we never thought possible. There is so much potential for change in medicine and so much impact and growth that can happen with translational medicine as the field becomes easier to access! Thank you to Dhruva Katrekar and his team in contributing to this pioneering work! #AI #Genomics #SyntheticBiology #Innovation
Our work on Evo was just published! Evo is a genomic foundation model that can read DNA's universal language to understand not just DNA itself, but also the proteins and RNAs it encodes. We've demonstrated this multimodal understanding by using Evo to generate novel functional CRISPR-Cas and transposon systems - marking the first time a language model has successfully codesigned both protein-RNA and protein-DNA complexes! https://lnkd.in/gV3X_3EZ
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If your research regularly needs 10-20 kb DNA constructs, join the webinar to learn about our technology that can make it happen. No more endless cloning!
🧬 Unlock the Future of DNA Assembly with DNA SCRIVENER! 🧬 We’re thrilled to announce the publication of our preprint on DNA SCRIVENER, our cutting-edge in vivo DNA stitching platform that brings a new level of efficiency to DNA construct assembly. Whether you’re tackling synthetic biology projects that contain biosynthetic gene clusters or long constructs with complex features, SCRIVENER provides a scalable and cost-effective solution. ✅ High-throughput assembly in 96- and 384-position arrays ✅ Sequence-perfect DNA constructs up to 23 kb, even with challenging regions ✅ Up to 98% accuracy ✅ Reusable DNA blocks without the need for PCR This platform is a game-changer for scientists looking to accelerate their DNA engineering efforts. Join us for an upcoming webinar where we will dive deeper into the capabilities of the platform and how it can streamline your workflows. 📰 Preprint: https://lnkd.in/gi8dbcbn 📅 Webinar Date: September 26 at 9am Pacific 🔗 Register Here: https://lnkd.in/gMv7YdhJ We look forward to discussing the future of DNA engineering with you!
Register to attend here - BacStitch DNA, Inc
https://bacstitchdna.com
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SBS technology from Illumina: the past, the present and the future of NGS How did NGS evolve over the years and where is it going - find out more listening to an interview with Pietro Gatti, Associate Director, Future Tech Strategy from Illumina.
Genomics in Focus: In Conversation with Illumina®
https://www.youtube.com/
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SBS technology from Illumina: the past, the present and the future of NGS How did NGS evolve over the years and where is it going - find out more listening to an interview with Pietro Gatti, Associate Director, Future Tech Strategy from Illumina.
Genomics in Focus: In Conversation with Illumina®
https://www.youtube.com/
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SBS technology from Illumina: the past, the present and the future of NGS How did NGS evolve over the years and where is it going - find out more listening to an interview with Pietro Gatti, Associate Director, Future Tech Strategy from Illumina.
Genomics in Focus: In Conversation with Illumina®
https://www.youtube.com/
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Associate Director, Collaborations and Applications | Genetics and Epigenetics | Multiomics
Adding unique molecule identifiers (UMIs, or 'you-mees' as one customer calls them :) ) to NGS library constructs offer a great way to get more utility from your data. PCR duplicate? Nope that's a unique molecule ! This is no different for our duet constructs, with benefits significantly scaling with depth e.g. targeted approaches. See our tech note below! Many hands were involved to get to this stage: credit to Walraj S. Gosal; Jens Füllgrabe; Minna Taipale; Paula Golder; Audrey Vandomme; Michael Hodgson; Aurel Negrea; Lisabet Andreasen; Ermira Lleshi, PhD; Abi Blackwell; Nikolay Pchelintsev; Timothy Beech https://lnkd.in/eDJBQw_G
Using UMIs with duet multiomics solution evoC reduces sequencing requirements and increases coverage
https://biomodal.com
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Tradeoffs in alignment and assembly-based methods for structural variant detection with long-read sequencing data. Long-read sequencing offers long contiguous DNA fragments, facilitating diploid genome assembly and structural variant (SV) detection. In this article, researchers systematically compare 14 read alignment-based SV calling methods (including 4 deep learning-based methods and 1 hybrid method), and 4 assembly-based SV calling methods, alongside 4 upstream aligners and 7 assemblers. https://hubs.ly/Q02qBX6s0
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Join our webinar on June 26 to learn about DRAGEN v4.3's next-gen multi-genome reference, new mosaic caller, and specialized MRJD callers. Discover how these innovations can enhance your genomic analysis accuracy and efficiency!
Illumina DRAGEN v4.3: Comprehensive coverage with leading edge innovations
illumina.com
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Join our webinar on June 26 to learn about DRAGEN v4.3's next-gen multi-genome reference, new mosaic caller, and specialized MRJD callers. Discover how these innovations can enhance your genomic analysis accuracy and efficiency!
Illumina DRAGEN v4.3: Comprehensive coverage with leading edge innovations
illumina.com
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1moFelicitaciones Jared