Ansa Biotechnologies, Inc.’s Post

Finally this is live! This single development will completely change the de-novo synthesis market. Close to zero complexity sensitivity at 5kbp!

This just In: Clonal DNA now up to 5kb! Head to our webportal and check out our assembled genes clonal product made from direct synthesis of 600+bp fragments! #teamANSA #DNA #syntheticDNA

Attention Network: now we will see the true power of enzymatic DNA synthesis!!! Historical complexity issues are out the window! Come check out how gene synthesis is about to change for the better.

10 years ago when I was still working in Jay Keasling's lab, I was asked to mentor a rotation student named Daniel Lin-Arlow. He had just come off a rotation in the Savage Lab where Dan had become fustrated that he was spending all his time cloning and therefore was not moving the science foward fast enough. Usually when taking on a rotation student, you offer them a couple of potential projects to work on and they pick one. But Dan wasn’t the usual rotation student. He had picked up some industry experience after undergrad and came back to academia with the goal of starting a company. Dan told me that he had his own project idea. He said that wanted to come up with a new way to synthesize long DNA molecules so that scientists didn’t have to waste their time building DNA. And then he was going to start a company to make long DNA molecules accessible to researchers. The Keasling Lab hadn’t worked on DNA synthesis before, but when you have a motivated and excited student, you have to let them run with their ideas. Dan quickly outlined how single molecule DNA synthesis could be faster and more accurate than existing synthesis methods. And within a couple of months we had a provisional patent application. Around that time I wrapped up in the Keasling Lab and went to work at Lygos. At Lygos we ordered a lot of DNA and we often struggled to get the sequences we wanted. Dan transistioned from single molecule DNA synthesis to enzymatic DNA synthesis, wrapped up his PhD, and founded Ansa Biotechnologies, Inc. A year ago I came full circle and joined Dan at Anasa. Over the last year I’ve had the chance to once again support Dan’s dream from 10 years ago — making long DNA accessible. Today we are announcing that Ansa is now selling a 5kb clonal DNA product. Because we build these constructs using our 600 bp synthesis products, we can make signficantly more complex DNA than our competitors. If you have promoters with repeated binding sites, UTRs with hairpin structures, AAVs with inverted terminal repeats, or any other DNA you have wanted but haven’t dared to order, then come give us a try.

It's been a long road from making 10mers by hand in grad school to this moment, but it's all been worth it-- our little idea from 2015 is now the basis of a gene synthesis service that can build 5 kb constructs faster and more reliably than anyone else on the market, and we're ready to scale. Has your experience with gene synthesis vendors felt a bit like flying on a discount airline, waiting at the gate while your flight gets delayed, then delayed again, and then cancelled? You don't have to settle for that experience anymore! Create an account at http://ansabio.com and get your 5 kb synthetic genes on time, regardless of sequence complexity.

My new teammate Mart Sooba is introducing SOLIScript ® reverse transcriptase!

Cell-Free DNA Isolation And Extraction Market It will grow to $2.49 billion in 2028 at a compound annual growth rate (CAGR) of 6.7%. Read More @ https://lnkd.in/gDu8Zkw3 #marketresearchreport #marketresearch #marketintelligence #marketreport #industryanalysis #TheBusinessResearchCompany #TBRC #CellFreeDNAIsolationAndExtraction

In case you missed it, I highly recommend watching this Ansa Bio webinar surrounding complex denovo DNA Synthesis. If you have ever had a fragment of block of DNA declined by a vendor, you need to watch this recorded webinar! https://lnkd.in/ghD64itE

Recovery of biological signals lost in single-cell batch integration with CellANOVA

Polymerase Chain Reaction (PCR) is a technique to make millions of copies of a specific DNA segment. It involves three main steps: denaturation (separating DNA strands), annealing (binding primers), and extension (synthesizing new DNA). PCR is used in research, forensics, and medical diagnostics to amplify DNA for various purposes. #PCR #PolymeraseChainReaction #DNA #Copies #Annealing #Denaturation #Extension #Amplify #Bioinformatics #Biotechnology #Lifescience