Aniket Sharma’s Post

The atomic unit is the living organism, supercharged by a genetic toolkit that allows humans to defy the laws of nature, creating never-before-possible products. Hear more from Kira Noodleman below ⬇ What we look for in our Biological Machines (BioM) vector are: 💵 Cost Reductions in all things DNA ⚗ Lab Automation 🤖 Advances in Machine Learning If you or someone you know is a founder innovating in any of our three vectors, please click or share the info to learn more about how to get funded with Bee Partners! Get Funded: https://lnkd.in/gu_nwqhn #venturecapital #VC #investor #investing #BeePartners

𝗔𝗹𝗽𝗵𝗮𝗙𝗼𝗹𝗱𝟯-𝗟𝗲𝘃𝗲𝗹 𝗔𝗰𝗰𝘂𝗿𝗮𝗰𝘆 𝘄𝗶𝘁𝗵 𝗕𝗼𝗹𝘁𝘇-𝟭 – 𝗡𝗼𝘄 𝗼𝗻 𝗡𝗲𝘂𝗿𝗼𝘀𝗻𝗮𝗽 The wait is over! The brilliant team behind Boltz-1 has released a truly open-source and commercial-friendly replication of AlphaFold3, and we’re thrilled to announce its integration into Neurosnap’s webserver. Boltz-1 achieves AlphaFold3-level accuracy in predicting 3D structures of biomolecular complexes and represents a significant leap in biomolecular modeling. It stands toe-to-toe with Chai-1 (a non-commercial-friendly AlphaFold3 replication) and even outperforms it in several benchmarks: • Protein-ligand predictions: Boltz-1 achieves an LDDT-PLI of 65%, compared to Chai-1’s 40%. • Protein-protein docking: Boltz-1 boasts DockQ > 0.23 in 83% of cases, surpassing Chai-1’s 76%. Building on the framework by Abramson et al. (2024), Boltz-1 introduces key innovations: • Efficient MSA pairing, structural cropping, and binding pocket conditioning. • Optimized diffusion training/inference and improved architectural flow. • Revised confidence modeling with fine-tuned trunk layers. By integrating Boltz-1 into Neurosnap, we’re bringing cutting-edge technology to everyone, everywhere. 🧬 Try it now: https://lnkd.in/ehXJDMN2 #biotech #bioinformatics #Neurosnap #Boltz1 #AlphaFold3

The first day of Accelerate24 (https://lnkd.in/gazTu_Tk) is packed with incredible workshops, including Advanced Bayesian Optimization Recipes for Real-World Applications using BayBE, led by Martin Fitzner from Merck KGaA, Darmstadt, Germany. Lisa Neuner, PhD, MBA Philipp Harbach Jacob Woodruff Marisa Gliege, PhD The BayBE package (https://lnkd.in/grAbQPkg) provides a comprehensive set of tools for a wide range of applications, including the optimization of biological experiments. Yimu Zhao and I plan to incorporate it into our Self-Driving Laboratory on Human Organ Mimicry, which we are developing within the Acceleration Consortium. Don't miss the chance to discover how these cutting-edge tools can redefine your approach to complex challenges! #Automation #SelfDrivingLab #Bayesian #Optimization #Accelerate24 #workshop #python #science

Just completed the Request for Ideas regarding Unblocking Scientific Publishing by Astera Institute. Not expecting a response, but the exercise helped me to distill the idea of #GlucoXe and will help with the white paper greatly. This summarize my description to the problem:

🌟 Exciting news! Just posted on my blog about why scientists should consider using the new My-Domains. Check it out here: [Link to the blog post] Let's keep the conversation going! #ScienceTech #DomainNames #BlogPost https://ift.tt/dMYFAXI

Incorporating GenAI into life sciences is an exciting prospect and goal for many for 2024. In our blog, Davide Deiana, PhD, and I discuss how addressing upfront MLR/PRC challenges with a GenAI Assistant can seamlessly integrate this technology into your business operations process. https://lnkd.in/gcqbAn9G

🌍 April 22 is #EarthDay (see comment with link to more info). How can we reduce our planetary footprint? 🧬 Biomanufacturing is one way: large-scale production from living organisms. To scale it up across industries - for example food, materials and medicine - we need new ways to work with biological systems. "Engineering biology" is how we design and build biological systems for industrial scale. Here's a peek into how we do it. What you're seeing below: 1280 experimental conditions, designed by machine learning algorithm, performed by robotic platform. 🤖 Our platform optimises conditions for cell growth, to help create new foods and therapeutics. 24/7 testing and optimising to find results that scale. Every day is earth day. #sustainability #biomanufacturing #engineeringbiology #alternativeprotein #cellularagriculture #cultivatedmeat

Excited to share Quibble’s latest advancements in revenue optimization for short-term rentals! 🚀 We’re pushing boundaries with innovative strategies to help property managers maximize their revenue potential in this ever-evolving industry. Check out our latest updates and join us in leading the future of STR management! 💼✨ #RevenueOptimization #ShortTermRentals #Innovation #TechInSTR #STRManagement

Last week I presented at my first Bits in Bio event! Really enjoyed interacting with the community, learning new names, and seeing familiar faces from Dimension's Protein x AI the week prior. Bay Area #techbio is sizzling! 🔥 Fantastic presentations and products by other speakers! Super smart crowd. Great questions about on-preming, finetuning, business models, and more. In addition to offering my perspective on bio-AI tooling and bottlenecks in synbio, I got to do a LIVE DEMO of some of the most time-saving features that we use on BioLM.ai: real-time predictions, embeddings search, response caching, autoscaling. Big thanks to Shantenu A., and 📸 to Natalie Ma, PhD! #bioml #synbio #finetuning #llms #bioai

COMING SOON -- turn your complex neural data into clear results with Axion Bio's powerful new neural analysis software   See what's possible with our upcoming software: ✅ Automatically import all experimental recordings to accelerate your workflow ✅ Simultaneously analyze & compare multiple files for in-depth evaluation ✅ Easily visualize complex data at a glance with new plot options  Sign up to get the latest updates on the neural analysis software via 🔗 https://bit.ly/3ZLmEBG #AxionBio #BioTech