Sergey Gribov

Some VC investors believe that brick and mortar - referring to a physical presence of some kind - should be avoided at all costs. Yet, the track record of clinic and hybrid care businesses in health care indicates otherwise. ==> One Medical (sold for $3.9 billion to Amazon), Oak Street (bought by CVS for $10.6 billion), Lifestance (IPO at $7.5 billion market cap), and PE-backed Premise Health (acquired by OMERS Private Equity for $1.1 billion) If a clinic is indicated as the optimal way to deliver care for that patient population, there are creative ways to build and operate them. Full article below with advice and strategies on how to build and operate hybrid clinics from my teammate Anarghya Vardhana from Maveron, Amir Dan Rubin from OneMedical Group, Steven Eidelman from Modern Animal and more!

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The (Healthcare) Ground Beneath Our Feet… This year it is likely that over $10 billion will be invested in the digital health sector – a robust amount, no doubt, but inconsequential when compared to the amount of capital tied up in healthcare real estate assets, which is estimated to be $1.2 trillion by Jones Lang Lasalle. Of that amount, approximately $790 billion is in the hospital sector while the remaining $490 billion is in medical office assets. It is estimated that there are 48.6k facilities with 3.4 billion square feet of healthcare real estate, 42% of which are owned by REITs and another 33% held by other private investment vehicles. Much of the digital health investment is meant to make the physical healthcare infrastructure more productive: greater operating efficiencies, greater patient throughput, more relevant personalized care models with better outcomes. As the healthcare system is being pushed to be more distributed to lower cost sites of care, accelerated now by the rapid proliferation of automation and AI capabilities, the potential impact on healthcare infrastructure assets will be profound. Thoughts on what that might look like... https://lnkd.in/eTfAdUbS #digitalhealth Flare Capital Partners

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https://lnkd.in/dDGfRVai "The amendments can be broken down into five core components, and while they don’t actively advance the fortunes of AI companies, they do make their lives easier. For example, one amendment will replace criminal penalties for perjury with civil ones, meaning the act now invokes no criminal charges for any violation and the legal repercussions of stepping out of line are significantly reduced.  The amended bill now also cuts the Attorney General’s ability to seek civil penalties “unless a harm has occurred or there is an imminent threat to public safety.” The amended bill makes the Attorney General’s office the main regulatory body for AI, rather than an originally proposed state regulatory body."

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Generally surprised to not see more hardware vendors in healthcare and life sciences partnering with AI-first companies. When the zone of genius of a company is hardware, it's difficult to imagine that same team achieving parity on an AI product – Apple may be the greatest example of success in this realm, and still has secured many AI capabilities via targeted M&A (Siri, Turi, Xnor.ai, Voysis, Inductiv). Given the importance of leveraged distribution models in the ossified industries of healthcare and life sciences, it seems there is untapped opportunity for more hardware manufacturers to partner and co-develop AI products with startups. Control over the way data is captured and processed is critical for building high quality training data sets, which creates an interesting feedback loop between hardware companies and potential AI-first startup partners. Interested to explore this further with folks in healthcare and life sciences hardware!

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This week Mikal Ventures brings you a 4-week breakdown of the US capital market with an emphasis on the Mikal verticals. Over the 4-week period ending April 15, just over 900 new companies were added, with 94,109 companies included in the US Health Tech, Med Tech, Fin Tech, AI Tech, and Ed Tech verticals. AI Tech again saw the greatest percentage of growth in new companies and transactions, weighing in at over double the vertical averages for the period. The US Fin Tech vertical again led the way in SEC Filings and news articles. Mikal Ventures publishes these stats on a rolling 4-week basis to provide a perspective on how the verticals and new startups move through time. We hope you find them informative and thought-provoking. VC Investors are always adjusting their "Play Book" with a variety of options for investing. Mikal Ventures is one of those alternatives, offering curated solutions to real world problems. Reach out if you have questions on how we can be of assistance and bookmark https://mikalventures.com/ for additional insights and information.

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🚀 Excited to partner with Noah Labs adesso ventures invests in the €3M round, led by Nina Capital and joined by DHZB Foundation as well as great angels. Current remote patient monitoring solutions often fall short, resulting in poor experiences for both patients and doctors due to inconsistent devices and software. Noah Labs aims to revolutionize this space with a patient-centric approach. Why we invested: 🫀 Team: The Noah Labs team is exceptionally strong, with deep connections to the medical field. Oliver brings invaluable founder experience from a previous MedTech venture. Marcus, the technical mind behind the AI-based voice analysis, has a research background at Harvard Medical School. Leonhard, with his medical expertise, has worked as a cardiovascular doctor and was previously head of medical at an RPM startup. 🎯 GTM: The team has developed an impressive GTM strategy and is executing it with precision. Monitoring of heart failure can be reimbursed through insurances in Germany, making it the optimal entry point for Noah Labs. Nevertheless, other diseases are already in demand and can easily be covered. 🏁 Vision: Besides using the existing RPM-tools such as ECGs and blood pressure monitors, Noah Labs follows a big vision of introducing voice-based detections of diseases using AI. Currently, several studies for their voice-based detection of heart failure are ongoing - among them a large study with reputable Mayo Clinic. This will set them apart from its competitors and create a unique value proposition. Read more here: https://lnkd.in/dkR6iCWU

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Two announcements re: our upcoming first-of-its-kind-event: a) 70+ Attendees are registered! b) The upcoming SiliconXL LaunchAthon is perfect for Job Seekers, Software Engineers and Boston-based Startups For more info or to register, visit ---> https://lnkd.in/efPxJ6Fk www - launchathons - com/boston The upcoming SiliconXL LaunchAthon is designed to provide job seekers with an immersive, hands-on experience that goes beyond traditional training. Through targeted AI coding workshops, attendees will dive deep into advanced AI tools and coding platforms, equipping them with practical skills that employers actively seek. These workshops allow job seekers to build real-world projects in collaboration with industry mentors, creating tangible portfolio pieces that showcase their abilities and problem-solving prowess. For those looking to enter the tech field, our LaunchAthon is an invaluable opportunity to gain relevant, hands-on experience that will make them stand out in a competitive job market. Furthermore, the collaborative environment encourages networking with potential employers and peers, giving job seekers a head start on forming connections that may lead to employment opportunities. For software engineers already in the workforce, our LaunchAthon’s workshops provide a vital opportunity to upskill and explore emerging technologies that might not be part of their current roles. The hands-on experience in AI-powered coding workshops offers a practical way to stay updated with industry trends, experiment with new tools, and learn innovative problem-solving techniques. These workshops encourage engineers to think outside their regular scope of work, sparking creativity and enhancing their adaptability to new challenges. Attending the SiliconXL LaunchAthon can add value not only to their current skill set but also to their role within their organization, as they bring back fresh insights and advanced knowledge that can be applied immediately to drive innovation in their day-to-day work. or startup entrepreneurs, the upcoming LaunchAthon offers an unparalleled opportunity to bring their ideas to life through hands-on experience with cutting-edge AI tools and collaborative workshops. Entrepreneurs will benefit from an environment where they can test, validate, and iterate on their concepts with the guidance of industry mentors and experienced tech professionals. These sessions are designed to accelerate the development process, providing valuable insights into product design, rapid prototyping, and market alignment. Beyond just building, entrepreneurs will also network with potential co-founders, partners, and investors, creating connections that can support their startup’s growth. LaunchAthon is more than an event; it’s a launchpad for entrepreneurial visionaries looking to create impactful, scalable tech solutions in a high-energy, supportive setting.

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This week Mikal Ventures brings you a 4-week breakdown of the US capital market with an emphasis on the Mikal verticals. Over the 4-week period ending September 16, 1,245 new companies were added, resulting in just under 98,450 companies included in the US Health Tech, Med Tech, Fin Tech, AI Tech, and Ed Tech verticals. US AI Tech again saw the greatest percentage growth in new companies at 30%, vs. the vertical average of 13% for the period. AI Tech also led the group in transactions and news articles. US Med Tech led in SEC Filings. Mikal Ventures publishes these stats on a rolling 4-week basis to provide a perspective on how the verticals and new startups move through time. We hope you find them informative and thought-provoking. VC Investors are always adjusting their "Play Book" with a variety of options for investing. Mikal Ventures is one of those alternatives, offering curated solutions to real world problems. Reach out if you have questions on how we can be of assistance and bookmark https://mikalventures.com/ for additional insights and information.

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At Two Bear Capital our definition of value-add, lead, early-stage investing is to form a true partnership with the founders we back. We believe that only a small fraction of our return potential comes from us “picking right” when we make our first investment into a company – the vast majority comes from how effectively we can actively help our brilliant founders over the ensuing 3-7 years in achieving the passionate, ambitious, and positive-impact goals that drive them.

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Excited for this one. Congrats to Alex Cohen and Hello Patient on their seed round announcement. Hello Patient stands to change the communication paradigm between patients and providers forever. Their generative AI call agent technology is tackling the tremendous admin burden of patient facing comms (scheduling, follow ups, referrals, prescription refills, etc). Massive opportunity and we think Alex and his team are expertly positioned to become market leaders. Max Ventures is thrilled to co-lead the seed round with 8VC and Bling Capital A great quote below from Alex highlighting the concept of "service as a software". Healthcare is a heavily service oriented industry - so the opportunity for step change is even more profound. The startup's approach is part of a paradigm shift where AI companies are offering service as software. "I'm a big believer that the right way to do this is through a managed services business. We're not building SaaS. I believe we can do this services as software where what was traditionally a services business now has software margins because I don't have to go employ a whole bunch of people to do the services under the hood," Cohen noted. https://lnkd.in/ehNN2AmW

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Shout out to Clark Valberg at Tiferes Ventures for sharing this article in his weekly AI briefing. "When clinicians are analyzing brain or tumor scans, instead of only looking at one patient’s image, they can now compare it simultaneously with those from millions of other patients...The cancer types that will derive the most benefit from AI assistance are those dealing with imaging data or high-dimensional data" https://lnkd.in/ec8UTJCn

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Exciting news from Monica Chopra, Jeffrey De Flavio, MD, Samantha Adelberg, and the rest of the Auxa Health team as they officially announce their $5.2M Seed round. The team's deep industry expertise and drive for change have led them to solve critical infrastructural friction to providing quality healthcare and adoption of value-based care. Auxa's AI benefit navigation platform is simplifying the complexities of healthcare by streamlining all of the fragmented and siloed data and information to make it actionable in real-time for healthcare organizations. For the 70% of Americans who aren't getting access to the health and social care benefits they deserve, Auxa's solution will be pivotal in enabling equitable care. We're thrilled to partner with co-investors Zeal Capital Partners, AlleyCorp, Laconia, and Chaac Ventures on this journey and look to share many more milestones ahead. Cc K50 Ventures, Ryan Bloomer, Daniel Vásquez, Nick Talwar, Stefanie Ng https://lnkd.in/dPDY7-Db

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"Equitable healthcare", and "democratized healthcare". I have spent a few years in the healthcare ecosystem, and sometimes sitting on the business side of things, these terms that I wholeheartedly endorsed and believed in, started to feel like jargon. In a "tech-enabled" healthcare world, true digital health innovation is rare, with many simply adding "AI-enabled" without substance. Which is why I am so glad to have met Viraj, who kind of got me out of my cynicism. My view had narrowed considerably, but looking at what Viraj is building and how, was refreshing and I am sure there are so many more people out there who are building health tech to realize equitable healthcare in India! Check out my short podcast episode with Viraj Kulkarni who is building Iyaso/Eloquent; an app that helps people overcome stammer and other speech disorders. Link to podcast: https://lnkd.in/gYwybbNb #Healthcare #DigitalHealth #Innovation #EquitableHealthcare #HealthTech

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Of note: Your health records are coming to new apps This in an interesting change, and a somewhat Epic change. All puns intended. If you don’t know, the leading medical record storage solution in the US is operated by Epic. A rather critical problem is that if you walk (well drive) between two hospital in the US, the medical records tend not to follow you, unless you carry a large Manila envelope. Having Epic (and others) via TEFCA allow export of records arguably allows you to only carry your phone, which is a very siginificant change. This also (arguably) opens up a huge new innovation sector. Epic is one of the organizations that has been helping the US federal government establish the Trusted Exchange Framework and Common Agreement, or TEFCA. The goal being to iron out both the legal and technical requirements for sharing patients' data at scale. Health-care data in the U.S. has historically been siloed and difficult to move around. Clinics, hospitals and health systems can store their information in a variety of formats across dozens of different vendors, and there hasn't been a trusted nationwide mechanism in place for transporting it securely. This means if a patient moves to a different state or visits a new hospital, their medical records tend not follow. PS. If you want appreciate how profitable the US medical sector is, Epic HQ has a restantant designed to look like Kings Cross from the Harry Potter movies. https://lnkd.in/g8NaWza8

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This analysis, at least anecdotally makes sense to me. In many situations, infringe and holdout is the least painful option for large infringers. The system enables it. - The plaintiff must allocate the time and $$ to assert, taking time and $$ away from selling and developing products. Even if they engage litigation financiers they are limiting their upside potential. - The infringer continues to infringe while employing stall tactics or simply relying on the painfully slow, overburdened legal system. - The cost benefit analysis for infringers - "infringe and pay lawyers" typically outweighs the cost of design around or license. - Enhanced damages and injunctions are rare. - Litigation insurance products reduce risk all around. "The Marcum report shows that there is indeed something wrong with the patent system in the United States but it’s not excessive litigation or patent trolls. The real problem is the inability of patent owners to enforce their rights against infringers. Given the difficulty of obtaining injunctive relief and the limited enhancement of damages, it is unsurprising that predatory infringement has become a standard business practice when, at worst, all an infringer can be expected to pay is a reasonable royalty and, at best, nothing at all."

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14 SiliconXL / DevAccelerator Powered Startups Launch in Stealth Providence, RI - Tuesday, September 24th The SiliconXL Startup Demo Day brought together a remarkable collection of AI-powered tech startups, demonstrating that the event was about far more than just polished pitch decks—it was a showcase of full-stack software engineering, AI, true innovation and customer-validated market demand. DemoDay Startups - Providence took place during RI Startup Week, with tremendous support from RIHub. Each startup, built from the ground up by technical founders, presented AI-driven solutions designed to solve real-world problems. This event emphasized the importance of market fit, with every startup validating their concept through direct interaction with potential users, showcasing not only their technical prowess but their ability to engage with and fulfill market needs. For many of the entrepreneurs showcased at the SiliconXL Startup Demo Day, this was their first experience building a full-stack application. In fact, virtually none of them had ever launched or scaled a tech startup before. Their journey from novice to technical founder was nothing short of transformative, a direct result of their time learning software engineering and AI under the mentorship of Claude Arnell Milhouse and Clifton Choiniere at DevAccelerator. Through DevAccelerator's intensive training and guidance, these founders have not only acquired the technical skills to develop cutting-edge AI solutions but have also gained the entrepreneurial mindset to launch and grow successful startups. This Demo Day is a testament to the profound impact that mentorship, education, and determination can have on an individual's ability to create something that will disrupt industries and transform their own lives in the process. What set this Demo Day apart was the potential for explosive growth, as SiliconXL is laser-focused on launching a tidal wave of startups across multiple markets in the upcoming months and years. From the buzzing streets of Boston and New York to the previously unknown startup market of Providence, the goal is clear: to create a tsunami of high-growth startup activity.  SiliconXL is also dedicated to ensuring that diverse communities not only have a seat at the table but are also leading the charge, amplifying voices that have been historically marginalized. With this Demo Day, it’s evident that SiliconXL is igniting a movement that will leave a lasting mark on the future of AI-powered innovation. Look for more events powered by DemoDay Startups in the months to come in a city near you (Hint: Boston, NYC and up to 16 more startups out of Providence this year). Let's GEEEEEKING Goooooo!!!! #Startups #TechnicalFounders #SoftwareEngineers #Providence #Boston #NewYork #Roxbury #Dorchester #Brooklyn #Queens #TheBronx #Harlem

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Embracing Ethical AI in Medicine: Key Insights from GIHF-AI's Latest Policy Briefing The latest policy briefing from the German Israeli Health Forum for Artificial Intelligence (GIHF-AI) highlights the ethical principles and trustworthiness essential for the successful integration of AI in healthcare. Here are the main points: 🔹 Trust and Transparency: Crucial for public acceptance and effective use of AI. Trust is built through transparent guidelines and continuous quality control. 🔹 Human Autonomy: AI should enhance, not replace, human decision-making. Ensuring that AI supports human autonomy is key to ethical AI use. 🔹 Continuous Quality Control: Regular updates and certifications are vital. This ensures AI systems are reliable and perform as expected in medical settings. 🔹 Data Management: Proper handling and legislative support for data management are necessary to maintain trust and protect patient privacy. 🔹 International Collaboration: Balancing innovation and regulation globally is essential. Countries like Israel, with advanced AI applications, contribute valuable insights to the global discourse. 🔹 Human Responsibility: Medical professionals must critically assess AI-generated results. Ensuring that doctors retain ultimate responsibility for patient care is fundamental. At Innoccu, we are committed to following the regulations and directives of the relevant authorities to create a solution that is also ethically oriented. For a deeper dive into how ethical AI can revolutionize healthcare, check out the full article here. 💡 #AI #Healthcare #Ethics #Innovation #GlobalCollaboration #TrustInAI https://lnkd.in/dk6a-GNK

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Incredibly excited to share our updated Healthcare AI thesis. This is not a market map – in 4,000 words, we dive deeply into the research, products, business models, and market entry points that are reimagining healthcare with AI. More specifically, we cover: • Translating AI research into real-world products • Mapping modalities (software, copilots, agents, services, diagnostics, therapeutics) to problems in healthcare • Designing AI business models that unlock billion-dollar markets • Closing current gaps in healthcare AI infrastructure • Distinguishing AI platforms from point solutions Let us know what you think ⤵️

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