Seth Winterroth

Interesting and innovative company. Proud to be an investor…

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We’re excited to announce that Pyka has raised $40M in Series B funding to accelerate the commercialization of their autonomous electric aircraft! Led by Obvious Ventures, with support from Piva Capital, Prelude Ventures, Metaplanet, and Y Combinator, this investment will expand Pyka’s impact in sectors like agriculture, cargo transport, and defense logistics. With commercial operations already underway across multiple continents and partners like Dole and Embraer, Pyka is transforming aviation while driving sustainability and decarbonization. ⚡✈️ More here from TechCrunch: https://lnkd.in/gGYfc824

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🤖 Robotics: What's new, and why now is the time to pay attention 🤖 The robotics sector is undergoing transformative changes, fuelled by advancements in AI, machine learning, and automation. 🚀 Read the latest MMC Ventures research to learn more. My colleagues Advika Jalan and Alexandra Reinert outline what’s driving the new wave of robotics innovation and why now is the perfect time to engage in the space. 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 🤖 #Automation #Robotics #AI

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Some VC investors believe that brick and mortar - referring to a physical presence of some kind - should be avoided at all costs. Yet, the track record of clinic and hybrid care businesses in health care indicates otherwise. ==> One Medical (sold for $3.9 billion to Amazon), Oak Street (bought by CVS for $10.6 billion), Lifestance (IPO at $7.5 billion market cap), and PE-backed Premise Health (acquired by OMERS Private Equity for $1.1 billion) If a clinic is indicated as the optimal way to deliver care for that patient population, there are creative ways to build and operate them. Full article below with advice and strategies on how to build and operate hybrid clinics from my teammate Anarghya Vardhana from Maveron, Amir Dan Rubin from OneMedical Group, Steven Eidelman from Modern Animal and more!

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Get to know our #hardtech portfolio! Check out the first post in our 'portfolio spotlight' series! Aspect Biosystems, led by CEO Tamer Mohamed, is a leader in regenerative medicine and 3d bioprinting! Learn more below 👇

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This is the beginning of big corporates in industrial and foundational industries solving the data availability problem to leverage the power of generative AI

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Med Tech in Focus:   Wearable Ultrasound Patch Offers Continuous Cerebral Blood Flow Monitoring Researchers at University of California San Diago have developed a postage-stamp sized ultrasound patch that can continuously monitor three-dimensional cerebral blood flow in real time. The technology is worn on the temple and is composed of silicon embedded with several layers of soft, stretchy electronics that produce and enhance ultrasound signals. Currently, a technician uses a Doppler ultrasound device on a patient’s head at specific times each day to monitor blood flow. That procedure has limits because such measurements can vary depending on the accuracy of the technician and data can fluctuate between readings.  The device is connected by cables to a computer and uses ultra-fast imaging and AI to collect and post-process data about the brain’s blood vessels. Patients who are undergoing and recovering from brain surgery could benefit from the device and it’s hoped that the continuous monitoring could tell if a patient is about to experience a stroke and provide an opportunity for timely intervention. VC Investors are always adjusting their "Play Book" with a variety of options for investing. Mikal Ventures is one of those alternatives, offering curated solutions to real world problems. Reach out if you have questions on how we can be of assistance and bookmark https://mikalventures.com/ for additional insights and information.

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Today, I was reminded of two remarkably prescient 1997 ACM, Association for Computing Machinery presentations: the first by Nathan Myhrvold and the second by Bran Ferran. If you are not a member of the ACM - I highly recommend joining. Nathan Myhrvold The future of software, the software industry, and Windows '47 https://lnkd.in/egMwYty Bran Ferran How IT will transform the experience of telling and listening to stories https://lnkd.in/gqF7C7TK

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What’s happening in healthtech? 💊🎉 💰Brandon Capital announced a $270m first close of its new life sciences fund 🚀ARM Hub (Advanced Robotics for Manufacturing) and MTPConnect launched a new Biomedical AI Sprints Accelerator (BASA) to elevate Aus's Biomedical Sector 🚑 updoc snagged $20m from ASX-listed Bailador Technology Investments (ASX:BTI) to expand 🧊 Southern Cryonics cryopreserved Aus's first-person 💉 GPN Vaccines raised $18m to advance a vaccine targeting Streptococcus pneumoniae 💊Telstra Health is acquiring the remaining 50% of Fred IT 🦠 Translational Research Institute Australia researchers bagged $4m from US Department of Defence for Parkinson’s treatments targeting the gut microbiome 🚨MediSecure, the e-script provider, entered administration following its cyber attack 🌏 The NHS is losing 1 in 5 departing UK doctors to Aus 🏛️ Medical Costs Finder, a $24m gov initiative for healthcare cost transparency, has seen only 20 doctors nationwide opting to list their fees 🌍 Aus is leading the way in tobacco control, with its anti-vaping measures recommended by the World Health Organization 🍄 AbbVie inked a US$2bn deal with Gilgamesh Pharmaceuticals aimed at developing next-gen therapies and novel neuroplastogens for psychiatric disorders 🌍 Google for Startups selected 24 startups across Europe, the Middle East, and Africa for its 'Growth Academy: AI for Health program'. Keen for the links & delicious deets?? 🍩🙌 Take a gander at last week's newsletter in the comments below👇😊 --- PS - if you liked this and are keen to join >7900 legends getting health tech and innovation news dropped direct to your inbox, subscribe to our newsletter, What the Health! 💜 📩 #healthtech  #health  #healthcare  #digitalhealth  #medtech  #biotech

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Mid-July we hosted a Robotics Founder & Funder summit that welcomed an insightful night with discussions surrounding topics including data collection, vertical versus horizontal integration, hardware, software and more. The full discussion from our VC panel is now live to read here: https://shorturl.at/YvtAS  Feel free to leave a comment on your thoughts and stay tuned for the startup panel blog coming soon! Below are some notable points from this panel:  - Robotics Investment Trends: Robotics investments have fluctuated with primary influence from labor shortages and technological advancements, but with the growing Western and Asian markets, a rebound is expected. - Vertical Integration in Robotics: Successful robotics companies often integrate both hardware and software. The debate continues on the effectiveness of software-only solutions versus integrated systems. - The Importance of Data + Challenges: There are limitations of simulations in robotics, which means real-world data is crucial for addressing edge cases and achieving high accuracy for the development of robust robotic systems. With significant data challenges, owning a strong data strategy is essential for success in the field. Once again, we’d like to share our appreciation for our wonderful panelists: Han H. of GV (Google Ventures), Sasha Ostojic of Playground Global and Xuhui Shao of Foothill Ventures, and our moderator Sahil Segal of Toyota Ventures. 

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Who doesn't love chatting about the frontier of Space?! Loved getting this insiders look from Epsilon3 CEO Laura Crabtree (ex-SpaceX, Northrop Grumman) as the industry reshapes into a lightening fast startup ecosystem for us to marvel. Small teams are lowering the cost to access space. Homegrown automation software is dramatically reducing team size -- as Laura puts it: "You won’t see 50 people in a control room for launch…you’ll see 5 controlling 50 different assets and a couple of 100 assets that are mostly operating on their own." Personally i'm keeping a close eye on the new interconnectedness between space and the broader economy will spark a flywheel of innovation. 🎙️ Listen in to our discussion (link in comments) as we release today -- 5YF#16: Space command reimagined, automating mission control, new deep tech hubs, interstellar missions, and the future of space operations w/ Epsilon3 CEO Laura Crabtree To infinity!

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Attention all women-led robotics startups! Don't miss the opportunity to pitch your robotics startup in front of top VCs and industry experts - winner receives a grand prize of $50K uncapped SAFE! 🤖💰 Apply now 👉 roboticspitchday.com Know someone who should apply? Tag below or DM me directly, let's empower more women in robotics! Brought to you by Boost VC x Spacecadet ❤️ Wiz 👨‍🚀 ‏‏‎ ‎Gus Domel, PhD Adam Draper Brayton Williams Emily Yu ‏‏‎ ‎ #womeninrobotics #womenindeeptech #robotics #startups

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Excited to share Marathon Venture Capital's investment in Eva Magnisali's DataForm Lab! Construction is large enough to be measured in GDP terms, yet remains a laggard in the adoption of automation. Our buildings are still constructed manually! Offsite manufacturing, i.e. assembling buildings in factories, provides the perfect canvas for putting automation to work – still, however, robots are nowhere to be seen... Eva studied architecture and robotics, and worked with design firms, developers and industry vendors, realising first hand what's keeping the industry stuck in the past. Then she got to work... Dataform Lab's software platform translates designs to production drawings and machine code, along with optimising processes and scheduling, essentially offering a modern operating system for construction factories. The company already works with some of the most prominent offsite manufacturers worldwide. Today it announces the completion of a GBP 1.1m Seed round led by Marathon. Eva and her team are on a mission to drive automation in offsite manufacturing. If you are excited about working at the intersection of technology and construction, get in touch! Building construction has been slow and expensive for far too long. Our next homes and schools may come from fully-automated factories, delivered at a fraction of today's time and cost. Keep an eye on Dataform Lab! https://lnkd.in/dVVfnudS

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🚀 Great to see SiPhox Health, one of our portfolio companies, featured in MIT News! The article captures how SiPhox is attempting to revolutionize home-based blood testing with cutting-edge silicon photonic technology. We co-invested in SiPhox through LongeVC back in 2023, alongside Intel Capital (leading the Series A), Khosla Ventures , and other prominent investors, because we recognized the disruptive potential of this technology. I think SiPhox’s approach to diagnostics is not just an incremental improvement—it’s a leap forward in accessibility, precision, and scalability. Here is my take what stands out in the SiPhox’s story: ✔️ Miniaturization of Lab-Grade Diagnostics: SiPhox has condensed what traditionally required large optical lab equipment into a single silicon photonic chip, leveraging advances in integrated optics and semiconductor manufacturing. ✔️ Scalability Through Silicon Photonics: Their chip fabrication can scale to produce billions of disposable chips per month using standard semiconductor fabs, enabling cost-effective, high-volume production. ✔️ Seamless Patient Experience: The "Nespresso-like" blood testing system integrates third-party blood sample collection (e.g., arm patches) with a reusable device and disposable cartridges, providing an intuitive, at-home diagnostic solution. ✔️ High-Fidelity Results: SiPhox's photonic immunoassay sensors offer lab-grade precision, tracking critical biomarkers for chronic disease management directly from home. ✔️ Platform Potential: Beyond diagnostics, SiPhox’s ecosystem offers integration with telehealth providers and third-party health services, paving the way for an Apple App Store-like platform for healthcare. This is healthcare democratization in action, making regular health monitoring as simple as brushing your teeth. Also, Kudos to Zach Winn of MIT for capturing this innovation so well. The future of healthcare is here, and we couldn’t be prouder to support SiPhox on this journey. 💡 Check out the article in the comments 👇 Image credit: MIT News and SiPhox Health

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Breaking down our latest newsletter section by section, starting with our expanded focus in Deep Tech: --- We have built expertise in the robotics sector, and will continue to double (and triple) down on investing in this category, but we have been increasingly finding that robotics is naturally steering us into two exploding adjacent areas: Aerospace, and Advanced Manufacturing (which we define as industrials, semiconductors, materials science, and energy production). Stepping back, this expansion makes perfect sense. Robotics is an inherently horizontal platform - meaning it can be applied productively across multiple industries. This quality, paired with the fact that robotics has long shown the highest TRLs of any deep tech technology, makes it a kind of “gateway” to other sectors in the hard sciences. Now with the recent breakthroughs in AI for robotics, growing semiconductor demand, and the resurgence of aerospace and defense tech, we are seeing a dramatic uptake of robotics and relevant technologies in both advanced manufacturing and aerospace. As an added bonus of the expansion, many of the founder (and funder) networks across these landscapes have natural overlaps and linkages. For AlleyCorp Deep Tech this means that we can be extremely helpful, knowledgeable, and engaged across all three sectors right away, and continue to be the best-in-class investing team across these categories.  --- More in our newsletter: https://lnkd.in/ewiTuYq6

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Hot take on a lot of early-stage digital health companies out there: You're not a tech company. Most tech-enabled care companies I've seen over the past two years are only tech-enabled in the sense that they use telehealth as their delivery mechanism for care. There are exceptions to this, of course - companies who build computer vision and applied AI tools to better the doctor-patient experience, companies who build tooling around risk scoring and stratification to enable more personalized medicine, companies who build truly novel intakes to better route patients to the appropriate care, etc. These companies have real technology chops and, if they sell it right to the market, can get credit for this from investors. But if you're truly a telehealth provider, you need to realize now that the goal post has shifted dramatically from 2021 and you're going to be valued at maturity at something like 3x EBITDA. That's profit. Not revenue. Throw a revenue multiple out the window. That's not the world we live in if you're a virtual doctor's office. Think of how that impacts venture math. If you're raising a seed round at $15M post-money (or $12M pre-money), it means you'll have to generate something like $150-200M in annual EBITDA to be a fund returner for your seed investors. Maybe even more with dilution, since telehealth businesses are not traditionally capital efficient and will likely need to raise material additional capital to reach that scale. You need to be ridiculously profitable (probably on $800M-$1B in annual revenue since you're likely going to be a 40% gross margin business). Here's the good news: you can set yourself up well (and probably be a contrarian founder relative to your peers), by talking about EBITDA growth and how you can grow into a fund-returning outcome based on realistic mature market comps. This will stand out for the investors you're pitching, even at the early stage. This is how you can beat the malaise of the tech-enabled care market. Focus on the right metrics and the right type of growth. You don't have to have all the answers (no founder does), but you need to make sure the ship is headed in the right direction. A focus on profitability for "tech-enabled care" (*ahem* telehealth) businesses is a good first step.

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Enjoyed giving this presentation today for Open Data Science Conference (ODSC) on Developing Equitable #AI Diagnostics. #ODSC2024 My slides can be found here: https://lnkd.in/gAbT4Yve

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🏦 OpenAI showed us what is possible when you apply AI to enterprise workflows on the office floor. 🏭📦 We think AI has the ability to fundamentally transform not just the office floor, but also the factory floor and the warehouse floor. Industrial applications of AI will supercharge productivity and drive efficiency gains while enhancing safety. It is with this thesis that Woven Capital is leading the Series C round for Third Wave Automation which is delivering impressive ROI for warehouses across the U.S. with their autonomous forklifts offering. Nicole LeBlanc, CPA Prashant Kumar Bothra Jarek Khoilian Read the full press release below -

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I could not be more excited to announce that Matter Venture Partners is joining Path Robotics on their journey by leading their latest round. Robotics is finally having its "mainframes to PC" revolution — AI is dramatically raising the limits of robotics in both capability and generalizability. And Path Robotics is bringing AI robotics to manufacturing in a big way. The core of this revolution is driven by the concept of task parity - a human in any job is doing more than just a single task, and a robot has to be similar. A waiter takes orders, pours drinks, runs credit cards. Welders do much more than just running a welding torch. That’s what made us so excited about Path Robotics - they started with robots that can weld the toughest, least precise jobs - like infrastructure for transportation and datacenter. Now they have robots that don’t just weld but can assemble parts, design fixtures, and solve problems autonomously. This is task parity in action. At Matter, we believe in the power of HardTech to solve real-world problems, and Path Robotics embodies that vision. I’m thrilled to be working with Andrew Lonsberry, Alex Lonsberry, and the entire team as they continue to push the boundaries of what’s possible with AI robotics in manufacturing. #AI #robotics #hardtech #manufacturing 

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