Matthew Covington, MD

Transthyretin Amyloid Cardiomyopathy (ATTR-CM) is a potentially fatal condition that stiffens heart walls. Want to help improve outcomes for patients with ATTR-CM? Our new clinical tool is designed to help clinicians identify cardiac amyloidosis early, offers links to heart failure information, red flags for ATTR, a diagnostic algorithm, and crucial resources. Check it out now: https://bit.ly/4fc9zXi #Cardiology #HeartHealth #MedicalTools #ATTRCM #ClinicianTools

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Check it out 👀 Our analysis of 700M+ data points can help you get more from your patient outreach.

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LCMC3 evaluated neoadjuvant atezolizumab in pts w/resectable #NSCLC & reported a 20% major PathR rate. The dev of AI-powered approaches in clinical settings may aid pathologists in clinical operations to support improved pt care & long-term outcomes. https://bit.ly/4akxjos #LCSM

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#HCP: Interstitial lung disease (ILD) is marked by progressive scarring of the lung tissue and is a common complication for autoimmune conditions.   Collaboration with rheumatologists and other healthcare providers to monitor lung health is crucial to early detection and accurate diagnosis. Learn more about #ILD at bit.ly/4eml51z.

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Most viewed in the last 7 days from JAMA Oncology: Is a ctDNA-guided adaptive de-escalation TKI strategy clinically feasible for radiologically undetectable advanced NSCLC after targeted and local consolidative therapy? https://ja.ma/3zd0TzH

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Identify the preferred therapeutic approach for individuals with advanced kidney failure.

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Adding perioperative nivolumab to neoadjuvant chemo improved event-free survival in patients with resectable #NSCLC, according to findings from the CheckMate 77T trial. #LCSM https://lnkd.in/e4WBuUe7

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#Chiropractic physicians consider the anatomic and physiologic relationships that produce neurologic deficits. In this image from Uchikado et al., we can appreciate the relationship between the IVD, capsular ligaments, the LF, and the under-appreciated transforaminal ligaments. Consider the effect of injury, and infra-foraminal adhesions on nerve roots, DRG, sinuvertebral and PPR. Consider the effect of intrusions on lymphatic drainage. Consider the chiropractic adjustments that may best benefit the integrity of the IVF. We discuss these relationships at length in our CE coursework at PostGradDC.com. Article: J Spine Surg 2020;6(2):405-414 | https://lnkd.in/ex7nXyNs

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Clinical dataset demonstrates that inferring human leukocyte antigen (HLA) genotypes is highly concordant to dedicated HLA testing. https://ja.ma/3B5sO5I

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Practice Point 2.2.3 underscores using a 2-year kidney failure risk threshold of >40% to determine modality education and timing for KRT preparation, including vascular access planning or transplantation referral. Predicting the optimal timing for these interventions in individuals with declining GFR is challenging. Premature vascular access planning may lead to unnecessary fistula placement, while delayed planning risks central venous catheter overuse at dialysis initiation. Studies advocate for risk-based thresholds, demonstrating comparable efficacy to eGFR alone. While the KDOQI vascular access guideline suggests a >50% risk threshold or eGFR <15 ml/min per 1.73 m², a >40% risk or eGFR of 15 ml/min per 1.73 m² is deemed acceptable for initiating vascular access referral based on current evidence. Lower risk thresholds, like >20%, enhance sensitivity and can prompt modality education or presurgical vascular access planning, particularly in centers with extended wait times. Link to the 2024 KDIGO Guidelines: https://lnkd.in/gDVT83EE #KDIGO2024 #ClinicalPracticeGuideline #ESRD #CKD #ESKD #Kidneydisease #RenalFailure #RenalReplacment #dialysis #hemodialysis #KRT #KidneyReplacementTherapy #CKDCare #ModalityEducation #VascularAccess #TransplantReferral #HealthcareGuidelines #MedicalDecisionMaking #KidneyHealth #PatientOutcomes #HealthcareManagement

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Study results do not support the systematic use of a magnetic resonance imaging-guided treat-to-target strategy among patients with #RA who are in #remission. https://brnw.ch/21wJp8v

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A recent Forbes article highlights an alarming reality: millions in the U.S. live in “cardiology deserts”—areas with no cardiologists—according to a research letter in the Journal of the American College of Cardiology. Nearly 46% of U.S. counties lack a practicing cardiologist, impacting around 22 million individuals, with the issue most severe in the Southern U.S., where heart health outcomes are notably poorer. Key Points: Rural Impact: 86% of fully rural counties have no cardiologists, limiting critical care access. Access Disparities: Over 16.8 million Black Americans reside in areas with little or no cardiology access. This underscores deep-seated healthcare inequities, demanding systemic change and innovative solutions. At Circadian Health, we understand these challenges and are committed to bridging these gaps. Our virtual-first approach delivers comprehensive specialty care for chronic conditions such as heart failure, diabetes, and sleep disorders. By leveraging smart devices and telemedicine, we reduce wait times for cardiologists, ensuring prompt diagnosis, evaluation, and monitoring—all from the comfort of home. This enables timely intervention and prevents avoidable complications, significantly improving health outcomes. As we advocate for equitable access, embracing technology is key to ensuring quality care reaches everyone, everywhere. #HealthcareAccess #CardiologyDeserts #CircadianHealth #Telehealth #ChronicCare #HealthEquity #SpecialtyCare

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Lowering serum urate to below 6 mg/dL in gout patients with chronic kidney disease stage 3 is not inferior to those who do not achieve this level with urate-lowering therapy. https://ja.ma/3CInyWj

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💗 MiRus™ Siegel TAVR: first in human results presented at New York Valves Five sequential patients with severe, symptomatic aortic stenosis (AS) were treated at the Instituto Nacional Del Torax in Santiago, Chile by Drs. C. Dauvergne, J. Sandoval and P. Yadav. Three patients had bicuspid aortic valves and two were tri-leaflet. Three patients had peripheral arterial disease with vascular access < 5.5 mm. There was no mortality or stroke at 30 days and no patients required a permanent pacemaker (PPM) or suffered vascular complications. At 30 days, the mean echo gradient was 6.7 mmHg; four of the five patients had no peri-valvular leak (PVL) and one bicuspid patient had trace PVL. Read more online: https://lnkd.in/e_9fv8MD 📰 Follow Medical Device Developments to receive the latest medical device news daily and to subscribe to our weekly newsletter #MedicalDeviceDevelopments #medicaldevices #medicalmanufacturing

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📰 LATE-BREAKER | Atrial Helix-Fixation Leadless Pacemaker: Initial Real-World Experience New data presented at #APHRS2024 highlights the safety and efficacy of our AVEIR AR Atrial Leadless Pacemaker. Learn more here: https://lnkd.in/gSMXd5aM Safety Info: https://bit.ly/4ey8UhV #AVEIR #Pacemaker #RealWorldData

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Long-term outcomes from the ADVANCE-DK Registry presented at TCT 2024 confirm the use of HeartFlow’s AI-enabled FFRCT and Plaque Analysis helps assess long-term risks, informing more personalized and effective treatment plans for patients with coronary artery disease. Read more about the positive seven-year data from ADVANCE-DK and a new study validating lesion-specific FFRCT in patients with NSTE-ACS here: https://bit.ly/4f0Q3wA.

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