#QOTD: No question for this one! I need more banter!! I'm looking at you, VaynerNation ;)
I absolutely hate when people send auto-messages after they've gained a new follower. I have actively un-followed most of you when you do this because it speaks to your intent on the platform. You're looking to scale social media on a platform like Twitter that's simply not scalable. 
Twitter is the only true social network because it functions like a town square. A place where you can jump into conversations without sounding/looking creepy. The other networks are pushing content where Twitter is still the place for actual conversation. 
When you go and auto-reply in a "town square," you're the same as the guy walking around just dishing out their business card at a conference or networking event. YOU'RE THE GUY THAT PEOPLE HATE. It's the wrong move. You're not putting any effort into engaging with people. You're auto-replying in the town square and providing no depth, no value.
What do you honestly think is going to happen when I receive that message? I'll tell you what's going to happen. I may sign up for your newsletter and you're going to email me and it's going to go to spam and I'm not going to engage. Why? Because there's no context established. That first taste, that first impression, all of a sudden is sh*t, and you've lost.