Dan Lord

Happy to announce LGC Biosearch Technologies has developed a proprietary client facing software for SNP calling available to end users purchasing AMP-Seq genotyping products as requested by our clients (https://lnkd.in/eEajGin4). Known as BiosearchCaller, the caller itself allows multiple models for SNP calling including de novo discovery of SNPs within amplicons and short indels. While we typically offer VCF file generation through our own pipeline, this will allow end users greater flexibility in choosing the model best suited for their organism. Works on both diploids and polyploids. See below for existing panels if you want to try it in your lab (parentage, genomic selection): #NGS #Genomics #SNP #GWAS #GEBV #GenomicSelection #Agriculture #Maize #HighThroughput #Genotype #Soy #Bovine #Pig #Canola #Sorghum #Strawberry #Wheat #Parentage

14

Gas Chromatography basic Learning. #gaschromatography #separation #chemical #pharmaceutical #analysis #qcanalysis #food #oil ##petroleum #environmental

10

1 Comment

For anyone that doesn’t fully understand the requirements for absence of specific microorganism testing for pharmaceutical products, register for our free webinar. We look forward to welcoming you all. #gmptesting #pharmaceuticals #micrbiologicaltesting

2

This application note demonstrates a comprehensive workflow, including sample preparation, consumables, data acquisition/analysis, and reporting for PFAS listed in EPA Method 1633 Draft 4 and in EU and UK regulations. Agilent Technologies #Bond #Elut #PFAS #WAX #SPE #Agilent #InfinityLab #PFCfree #HPLC #conversionkit #Infinity #LC #6495D #TQ #LCMS #SWARM #SLIMS #EPA #EPA1633

18

1 Comment

🆕Check out the latest technical poster from LGC Standards: 𝗖𝗵𝗮𝗿𝗮𝗰𝘁𝗲𝗿𝗶𝘀𝗮𝘁𝗶𝗼𝗻 𝗼𝗳 𝗶𝗺𝗽𝘂𝗿𝗶𝘁𝘆 𝘀𝘁𝗮𝗻𝗱𝗮𝗿𝗱𝘀: 𝗛𝗼𝘄 𝗴𝗼𝗼𝗱 𝗶𝘀 𝗴𝗼𝗼𝗱 𝗲𝗻𝗼𝘂𝗴𝗵? https://okt.to/lsr8NJ This poster explores ✅key methods for Impurity reference standards (IRS) characterisation, including system suitability testing, peak identification, and the validation of specificity parameters. It also provides ✅guidance on using separation techniques like HPLC and GC for purity assessment and highlights the importance of accurate quantification to ensure compliance with regulatory standards. #ImpurityStandards #impurityTesting #PharmaceuticalAnalysis #ReferenceStandards

8

Our recording of the 'Advances in Bio-Automation' panel discussion has arrived! The session features speakers from Nucleate UK, Recursion, Synteny, twig and Automata 🥼 Watch the video here ➡️ bit.ly/3KYKSjn #BioTech #LabAutomation #PanelDiscussion

6

Read the latest Chromatography Today ebulletin...in this issue we look at how #AI raised alarm on invasive hornet species; the push for the #digitalisation of the #pharmaceuticalindustry; and if NIR #spectrometers could solve the #plasticrecycling problem. Also...are you aware of the harmful effects of #microplastics and nanoplastics on human health? New research cites them as a significant threat ☠️ 👉 https://ilmt.co/TL/ZRqz Plus all the latest #chromatography products and news with a free subscription 👉 https://ilmt.co/TL/pN9A #PFAS #ForeverChemicals #hplc #sciencenews #scientificresearch #lifesciences

2

Want to catch bacterial contamination early in your CHO cell cultures? Aber Instruments Ltd's webinar (link below!) explores how conductivity & dielectric spectroscopy can help with real-time monitoring & process automation. https://lnkd.in/eQPxdiGj #WebinarAlert #bioprocess #biotechnology #ProcessAutomation #CellCulture #ContaminationDetection #learning

4

Always on the hunt for your next podcast? 🎧 Looking for a new and exciting blog to read? 📰 Look no further! 🎉 Organomation's very own David Oliva is the host of Concentrating on Chromatography, where scientists and researchers offer insights into the latest #chromatography and #massspectrometry techniques and topics. Get a sneak peak in our article below, and don't forget to head over to https://lnkd.in/e6NMEgXG for more.

2

Are you seeking an efficient method for the downstream purification of your AAV?   In a recent article, Buzz Lobbezoo of Thermo Fisher Scientific and Spyridon Gerontas of Pharmaron Biologics (UK) Ltd discuss the results of a case study using a scalable universal-capture resin for the purification of AAV harvest material. Find out how this resin performed and how it can help you simplify your downstream purification process for AAV here. https://lnkd.in/e7NrZudU   #bioprocessing #bioproduction #viralvectors #purification #chromatography #pharmaronbiologics

19

Scientists are a busy bunch, so we know the pressure of doing everything in your power to speed things up a little. Abcam recently developed their 384-well SimpleStep ELISA kit for this very reason: these high-throughput kits allow you to process samples four times quicker than traditional ELISA while still delivering high-quality, specific results. https://bit.ly/3KZkMgn .

4

NICE already recommended Genedrive as the point-of-care test of choice in its draft guidance before clopidogrel administration in the management of Ischemic Stroke (IS) and Transient Ischaemic Attack (TIA) patients. Really great achievement outperforming the laboratory test with respect to accuracy! #diagnostics #pharmacogenetics #PGx #pointofcare #POCT #stroke #nhs

6

1 Comment

Are you seeking an efficient method for the downstream purification of your AAV?   In a recent article, Buzz Lobbezoo of Thermo Fisher Scientific and Spyridon Gerontas of Pharmaron Biologics (UK) Ltd discuss the results of a case study using a scalable universal-capture resin for the purification of AAV harvest material. Find out how this resin performed and how it can help you simplify your downstream purification process for AAV here. https://lnkd.in/e7NrZudU   #bioprocessing #bioproduction #viralvectors #purification #chromatography #pharmaronbiologics

3

With Biological Safety Levels (BSL), many gene therapy developers and manufacturers aim for BSL I in the manufacturing process. But as Aldevron’s Cody Grasswick points out, there are reasons to consider BSL II when some regulations and controls come into the mix. https://lnkd.in/gNeZZ-Pk

18

Congratulations to the Nanocomp team for Commercial Activity of the Year award received at the SSPC, SFI Research Centre for Pharmaceuticals Annual Symposium this week at the University of Limerick. Working with Sarah Hudson on stage 1 of this project was arduous and a drag…as you can see from our faces in the picture below 😃. I mean, you can’t fake that kind of “chemistry”! I loved working with Nanocomp team every day even though they spoke a foreign language to me. I had to learn a whole new field of science from scratch. In every step they patiently taught me the basics, answered my silly questions, and through it all these highly respected and established scientists were always curious and open about what I had to say from the commercial perspective. That is why after a year’s hiatus, I decided to join them again. When I was considering all the opportunities that came my way in the last few months, I prioritized team dynamic and intellectual challange over other factors. Let’s face it, life is not getting any longer. It’s good to know what you need to get you out of bed every day. (Plus I get to say “plasma” in serious sentences a couple of times a week and for a Trekkie that’s reason enough no?!) Nanocomp is a novel solid drug formulation technology that can potentially enable more therapies to reach the market with significant manufacturing efficiencies and a smaller gentler environmental footprint. Considering the number of therapeutic molecules in the pipeline that are poorly water soluble, this is a very worthwhile venture to explore. I’ll spend the next year finalizing the business plan. Congratulations to the Nanocomp team on this award that is a testament to your dedication and hard work on this project: professors kieran hodnett Peter Davern Åke Rasmuson and the young scientists who built up an impressive body of data to support our claims: Ajay Kumar, Promita Bhattacharjee, Marta Bergillos Ruiz and Peuli Ghosh. Many thanks for SSPC, SFI Research Centre for Pharmaceuticals for the award and for investing so much in the supportive environment that allows innovation to thrive. And of course many thanks to Enterprise Ireland for generously funding this project and enabling the Nanocomp team to come together and do more. Majella Maher our EI advisor and partner in crime, thank you for keeping us on the righteous path and enabling this project every step of the way. You should be in this picture. We will miss you dearly as we finish stage 2. #Chemistry! Here we go again (literally and figuratively). And Bravo Nanocomp. #SSPC15 #UL

150

7 Comments

I am blowing the Qkine trumpet 🎺 🎺 !! We can be guilty of being a bit too British and humble about our products, but since we released #ActivinE it has proven to be very popular. Even more so than expected! After speaking with customers it is clear that there is a demand for a bioactive [see image] and reliable source of Activin E which we can absolute provide. So, if you are using this #protein in your work and have thus far struggle to find consistency with your supply please reach out to Qkine. #Activin #growthfactors #stemcells #immunology #cancerresearch

31

At Chromatography Direct our aim is to make quality #chromatography supplies more accessible to the scientific community without stretching your budget. Whether you're in a commercial lab or academia, we understand that time, consistency & cost-effectiveness are key to driving innovation and research. That's why we've curated a range of products that ensure you don't have to compromise on quality for affordability. UCT Sample Preparation Products - https://hubs.li/Q02HB6vt0 Eureka Ready-to-use Clinical Kits, References & Standards - https://hubs.li/Q02HBcTL0 Chromatography Direct Instrument Spares - https://hubs.li/Q02HB5hX0 Vials, Caps, Syringe Filters, Columns & More - https://lnkd.in/evzi4XB #ScienceForLess #ResearchInnovation #QualityScience #AffordableScience #LabLife #ChromatographyDirect

2

🔗 Great start to the week yesterday visiting Geoff Molyneux at Shout Connect. Excited to see where our networking takes us. What is Liquid chromatography? 👩‍🔬 A technique used to separate, identify, and quantify components in a mixture. It involves passing a liquid sample through a column packed with a solid adsorbent material. Different components in the sample interact differently with the adsorbent and elute at different times, allowing for their separation and analysis. 🥃 Imagine you have a mixture of coloured inks and place a drop at the bottom of a strip of paper, then dip the paper into water. As the water travels up, it carries the inks, which move at different speeds and separate into distinct bands of color, illustrating how liquid chromatography separates components in a mixture. 🔎 Real life applications include Pharmaceuticals, environmental testing, food and beverage testing, clinical diagnostics, forensics, chemical research. For more information on our Liquid Chromatography products please get in touch. #networKingwithstephKing #LCMS #WatersCorporation #network #NorthWest

17

3 Comments

https://lnkd.in/eMnPdwZs Read the latest blog on the comparison of molecular detection Techniques: SYBR Green Vs. TaqMan written by our expert Product Manager John Probert at 2BScientific Ltd. #TaqMan and #SYBR Green #PCR techniques are critical for research in molecular biology, driving advancements in investigations and diagnostics. Here’s why they're essential: Gene Expression Analysis and Biomarker Detection: SYBR Green PCR for screening, followed by TaqMan PCR for precise quantification and validation. Microbial Detection and Oncology: SYBR Green PCR for broad screening, TaqMan PCR for accurate quantification of specific targets. Epigenetics Studies, Pharmacogenomics, and Personalised Medicine: SYBR Green PCR's early assessment complements TaqMan PCR's precision, aiding informed treatment decisions. Check out the detailed article from 2BScientific covering the utilisation of TaqMan and SYBR Green, along with our selection of superior research reagents suitable for PCR and various research applications. #hereforyou #2bscientific #molecular

7