Shaquille O’Neal Jokes that He's 'Ozempic FBI' as He Teases Charles Barkley for His Weight Loss: 'I'm Snitching'

Shaquille O’Neal is poking fun at his friend Charles Barkley’s use of weight loss drugs.

On Tuesday’s episode of Inside the NBA, Jalen Rose asked O’Neal, “You told [Alonzo Mourning] you’re not drinking milk?” before the former Lakers star, 52, clarified, “Low-fat milk.”

“You already got the fat cut,” Barkley, 61, quickly chimed in and teased.

“Ozempic still looking for your ass,” O’Neal said to Barkley, teasing him for his use of weight loss drugs. “Ozempic, I’m snitching, he’s right here! Ozempic FBI, he’s right here!”

The former NBA stars all burst into laughter at the joke.

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In May 2023, Barkley appeared on the Dan Patrick Show and revealed that he was taking  Mounjaro, an FDA-approved prescription medication for people with type 2 diabetes. It's a brand name for tirzepatide — also known as Zepbound — which has been proven to be highly effective for weight loss by reducing appetite and improving how the body breaks down sugar and fat. 

Mounjaro is similar to Ozempic and Wegovy — brand names for semaglutide. They work in the brain to impact satiety and have been trending in Hollywood circles for weight loss.

"I'm working out, I'm taking my shot once a week," Barkley said at the time, sharing that he’s lost 62 lbs. "I started at 352 [lbs.] and I'm down to 290. I'm starting to feel like a human being, not a fat ass anymore."

He then said his goal weight was 270 lbs.

O’Neal is often teasing Barkley about his use of weight loss drugs. The pair have both been working on their respective weight-loss journeys.

On Nov. 20, the host of Inside the NBA posted a video participating in the viral "suspect challenge" trend. In the clip, O’Neal is filming in Barkley and says, “Suspect is wanted by Ozempic ’cause the drugs don’t work on his fat ass.”

Barkley laughed and then replied, “Mounjaro, fool!”