Frasier: Get a First Look at Season 2's Starry Guest Lineup — Including Peri Gilpin's Return as Roz! (Exclusive)

PEOPLE has the exclusive first look at this season's memorable guest stars, including Patricia Heaton, Yvette Nicole Brown and even Kelsey Grammer's real-life daughter Greer Grammer

Nicholas Lyndhurst as Alan, Patricia Heaton as Holly and Kelsey Grammer as Frasier in Frasier, episode 9, season 2 streaming on Paramount+, 2024.
Patricia Heaton and Kelsey Grammer on 'Frasier.'. Photo:

Chris Haston/Paramount+

The good doctor is back — and with some famous friends!

In just a week, Kelsey Grammer will step back into the iconic role of Dr. Frasier Crane for season 2 of Frasier, which premieres on Sept. 19.

While the Paramount+ revival’s first go-around welcomed back two familiar faces — Bebe Neuwirth as Dr. Crane’s thorny ex Lilith and Peri Gilpin as his former radio show producer Roz — this new season promises a star-studded lineup of guest stars to help keep the laughter flowing, including Patricia Heaton, Yvette Nicole Brown, Rachel Bloom, Amy Sedaris, Carol Burnett, Harriet Sansom Harris, Edward Hibbert, Dan Butler and Kelsey's daughter Greer Grammer.

Gilpin is also set to return again in the same role that made her so beloved with fans.

Below, PEOPLE has the exclusive first look at the celebrity guest stars appearing on the comedy in the coming months.

01 of 10

A Casual Toast

Jess Salgueiro as Eve, Jack Cutmore-Scott as Freddy, Peri Gilpin as Roz, Patricia Heaton as Holly and Kelsey Grammer as Frasier in Frasier episode 9, season 2 streaming on Paramount+, 2024.
Jess Salgueiro, Jack Cutmore-Scott, Peri Gilpin, Patricia Heaton and Kelsey Grammer in season 2, episode 9 of 'Frasier.'.

Chris Haston/Paramount+

In the season 1 finale, Roz (Peri Gilpin) paid Frasier an unexpected visit during his Christmas party but decides to stick around Boston a little longer.

Here, the former producer returns for season 2 and finds herself locked in conversation with Eve (Jess Salgueiro), Freddy (Jack Cutmore-Scott), Holly (Patricia Heaton) and Frasier.

02 of 10

Talk to the Hand

Nicholas Lyndhurst as Alan, Patricia Heaton as Holly and Kelsey Grammer as Frasier in Frasier, episode 9, season 2 streaming on Paramount+, 2024.
Patricia Heaton and Kelsey Grammer in season 2 episode 9 of 'Frasier.'.

Chris Haston/Paramount+

Heaton's appearance on Frasier marks the first time she and Grammer have been onscreen since their 2007 Fox sitcom Back to You.

This time around, the two-time Emmy-winning actress plays Holly, a "down-to-earth" and "unpretentious" Boston native who tends bar at restaurants and events.

03 of 10

Turning the Tables

Kelsey Grammer as Frasier and Patricia Heaton as Holly in Frasier, episode 9, season 2 streaming on Paramount+, 2024.
Kelsey Grammer and Patricia Heaton in season 2 episode 9 of 'Frasier.'.

Chris Haston/Paramount+

While Frasier and Holly may have different backgrounds, Frasier is intrigued by (and attracted to) Holly, who isn't easily impressed by intellectuals.

04 of 10

Sharing a Chuckle

L-R: Kelsey Grammer as Frasier and Amy Sedaris as Dr. Ayton in Frasier, episode 4, season 2 streaming on Paramount+, 2024.
Kelsey Grammer and Amy Sedaris in season 2 episode 4 of 'Frasier.'.

Chris Haston/Paramount+

Amy Sedaris portrays Dr. "Doc" Stathos, a municipal therapist with a down home, scattered veneer who works with the firefighters at Freddy's firehouse. She also happens to be a huge fan of Frasier's from his radio show days.

05 of 10

What a Surprise!

Yvette Nicole Brown as Monica, Toks Olagundoye as Olivia and Rafael Cebrián as Augustine in Frasier, episode 7, season 2 streaming on Paramount+, 2024.
Yvette Nicole Brown, Toks Olagundoye and Rafael Cebrián in season 2 episode 7 of 'Frasier.'.

Chris Haston/Paramount+

After Olivia (Toks Olagundoye) name-dropped her sister several times during season 1, Monica (Yvette Nicole Brown) finally pops up this season. But she may be in for an unexpected surprise or two.

06 of 10

Deliciously Devious

Harriet Sansom Harris as Bebe in Frasier, episode 5, season 2 streaming on Paramount+, 2024.
Harriet Sansom Harris in season 2 episode 5 of 'Frasier.'.

Chris Haston/Paramount+

Once described on the original NBC sitcom as "Lady Macbeth without the sincerity," Frasier's agent Bebe Glazer (Harriet Sansom Harris) was arguably one of the show's smartest-written recurring characters.

Episode 5 of Frasier sees the delectable return of Bebe with a Bloody Mary cocktail in hand.

07 of 10

Like Mother, Like Daughter?

Kelsey Grammer as Frasier, Rachel Bloom as Phoebe and Harriet Sansom Harris as Bebe in Frasier, episode 5, season 2 streaming on Paramount+, 2024.
Kelsey Grammer, Rachel Gloom and Harriet Sansom Harris in season 2 episode 5 of 'Frasier.'.

Chris Haston/Paramount+

Bebe's reunion with Frasier includes an introduction to her daughter Phoebe Glazer (Rachel Bloom).

Bloom told Entertainment Weekly her character is a "very cultured kind of opera fan."

"She and Frasier hit it off in a way that he questions if maybe they're related," Bloom teased.

08 of 10

Being a Father

Kelsey Grammer as Frasier, Greer Grammer as Alice, Jack Cutmore-Scott as Freddy and Jess Salgueiro as Eve in Frasier, episode 6, season 2 streaming on Paramount+, 2024.
Kelsey Grammer, Greer Grammer, Jack Cutmore-Scott and Jess Salgueiro in season 2 episode 6 of 'Frasier.'.

Chris Haston/Paramount+

Grammer's real-life daughter Greer Grammer swings by in episode 6 as Roz's daughter Alice, who recently moved to Providence to study architecture. Alice is apparently eager to catch up with Freddy, even if it means complicating his love life.

While Alice is all grown-up now, that doesn't stop Frasier from being a little paternal and helping her take off her coat.

09 of 10

A Reunion of Radio Jockeys

Dan Butler as Bulldog and Kelsey Grammer as Frasier in Frasier, episode 8, season 2 streaming on Paramount+, 2024.
Dan Butler and Kelsey Grammer in season 2 episode 8 of 'Frasier.'.

Chris Haston/Paramount+

As host of the Gonzo Sports Show on KACL radio on the original Frasier, Bob "Bulldog" Brisco (Dan Butler) couldn't be more different from the good doctor.

But the two have eked out a begrudging respect, and in episode 8, Bulldog and Frasier reconnect at KACL radio.

10 of 10

Just Like Old Times

Kelsey Grammer as Frasier, Edward Hibbert as Gil, Dan Butler as Bulldog, and Peri Gilpin as Roz in Frasier, episode 8, season 2 streaming on Paramount+, 2024.
Kelsey Grammer, Edward Hibbert, Dan Butler and Peri Gilpin in season 2 episode 8 of 'Frasier.'.

Chris Haston/Paramount+

In a full circle moment, Frasier finds himself in his old recording booth at KACL radio with Roz, Bulldog and food critic Gil Chesterson (Edward Hibbert), who hosted the radio show "Restaurant Beat" on the original sitcom.

Never miss a story — sign up for PEOPLE's free daily newsletter to stay up-to-date on the best of what PEOPLE has to offer​​, from celebrity news to compelling human interest stories.

Season 2 of Frasier premieres Thursday, Sept. 19 on Paramount+.

Comments
All comments are subject to our Community Guidelines. PEOPLE does not endorse the opinions and views shared by readers in our comment sections.

Related Articles