About
I am the Head of Innovation at Magic Valley, a startup that is producing cultivated meat…
Activity
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🌱 Excited to share that Magic Valley is sponsoring Food Frontier’s AltProteins 24 conference in Melbourne next month! Join us to explore why…
🌱 Excited to share that Magic Valley is sponsoring Food Frontier’s AltProteins 24 conference in Melbourne next month! Join us to explore why…
Liked by Jacob Goodwin
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Melbourne startup Alt.Leather has created a world-class, patentable leather alternative made entirely from plants. With investment support from the…
Melbourne startup Alt.Leather has created a world-class, patentable leather alternative made entirely from plants. With investment support from the…
Liked by Jacob Goodwin
Experience
Education
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Griffith University
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During my PhD, I focused on how age related factors in neurobiology act synergistically to generate high molecular weight alpha-synuclein aggregates, similar to those seen in Parkinson's disease patients.
This project involved the characterisation of alpha-synuclein oligomeric structures in vitro using recombinant protein and scanning electron microscopy, along with a cell culture model using confocal microscopy to assess the aggregation of alpha-synuclein in response to increased…During my PhD, I focused on how age related factors in neurobiology act synergistically to generate high molecular weight alpha-synuclein aggregates, similar to those seen in Parkinson's disease patients.
This project involved the characterisation of alpha-synuclein oligomeric structures in vitro using recombinant protein and scanning electron microscopy, along with a cell culture model using confocal microscopy to assess the aggregation of alpha-synuclein in response to increased intracellular calcium and oxidative stress, two factors that increase in the brain as we age.
The outcome of this research was two first author, two co-author research publications and one review article. -
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Activities and Societies: The Molecular Sciences Society
This project involved the development of a Drosophila model system of Nijmegen Breakage Syndrome (NBS). Mutations in the NBS1 gene result in impaired DNA double strand break repair. NBS1 mutants were inserted into full length wt-NBS1construct +/-GFP in plasmids allowing for either embryonic or adult expression of protein constructs. Constructs were used to generate transgenic Drosophila lines expressing mutant NBS1 proteins, to cross with NBS1 null drosophila to assess the viability of…
This project involved the development of a Drosophila model system of Nijmegen Breakage Syndrome (NBS). Mutations in the NBS1 gene result in impaired DNA double strand break repair. NBS1 mutants were inserted into full length wt-NBS1construct +/-GFP in plasmids allowing for either embryonic or adult expression of protein constructs. Constructs were used to generate transgenic Drosophila lines expressing mutant NBS1 proteins, to cross with NBS1 null drosophila to assess the viability of Drosophila as a model for NBS.
Licenses & Certifications
Volunteer Experience
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Siemans Science day demonstrator
Griffith University, Australia
- Present 14 years
Education
I was a demonstrator at the Siemans Science day at Griffith University where we took early high school students and gave them practical laboratory experiences to promote science as a career path.
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Biomedicum Social committee member
Karolinska Institutet
Science and Technology
A new research center is currently being constructed at Karolinska Institutet that will house 5 different departments that have previously been working in isolation. At the Biomedicum research building all departments will be housed together to increase the collaborative work environment and to improve scientific discourse.
I was involved in planing and running a Biomedicum social event to facilitate meeting and encourage interaction between the 5 departments before the move in 2018.
Publications
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Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer
Antioxidant Redox Signalling
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Indoleamine-2,3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans
Free Radical Biology and Medicine
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Potassium depolarization and raised calcium induces α-synuclein aggregates.
Neurotoxicity Research
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Raised calcium and oxidative stress cooperatively promote alpha-synuclein aggregate formation
Neurochemistry International
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Raised calcium promotes α-synuclein aggregate formation.
Molecular and Cellular Neuroscience
Languages
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English
Native or bilingual proficiency
More activity by Jacob
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🌿 Inspiring Weekend at Edgar's Mission! 🐷 I recently had the privilege of returning to Edgar's Mission, a farm animal sanctuary dedicated to…
🌿 Inspiring Weekend at Edgar's Mission! 🐷 I recently had the privilege of returning to Edgar's Mission, a farm animal sanctuary dedicated to…
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I love speaking at these events, surrounded by ambitious, like-minded individuals all working towards a common goal! Don’t miss Eating Plants…
I love speaking at these events, surrounded by ambitious, like-minded individuals all working towards a common goal! Don’t miss Eating Plants…
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Did you know that 19% of Australians consider themselves flexitarians? 🌱 100% of the respondents in our consumer research who fit a “flexitarian”…
Did you know that 19% of Australians consider themselves flexitarians? 🌱 100% of the respondents in our consumer research who fit a “flexitarian”…
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📣 Brinc Portfolio News Another week, another series of achievements from our portfolio companies! ⭐️ EyeROV (IROV TECHNOLOGIES PRIVATE LIMITED)…
📣 Brinc Portfolio News Another week, another series of achievements from our portfolio companies! ⭐️ EyeROV (IROV TECHNOLOGIES PRIVATE LIMITED)…
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We have some very exciting news: we’re announcing the launch of our waitlist for the exclusive opportunity to try Magic Valley’s cultivated…
We have some very exciting news: we’re announcing the launch of our waitlist for the exclusive opportunity to try Magic Valley’s cultivated…
Liked by Jacob Goodwin
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❓Electric vehicles and cultivated meat ❓The Coca-Cola Company and Four Pillars Gin These are just two analogies discussed in this conversation about…
❓Electric vehicles and cultivated meat ❓The Coca-Cola Company and Four Pillars Gin These are just two analogies discussed in this conversation about…
Liked by Jacob Goodwin
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A bit delayed but I finally got my first project review paper published - on cultivated crustacean meat (CCM)! Although it covers a lot of ground, in…
A bit delayed but I finally got my first project review paper published - on cultivated crustacean meat (CCM)! Although it covers a lot of ground, in…
Liked by Jacob Goodwin
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Things are (literally) coming together over at our Ferntree Business Park Site! We can't wait to be able to open our doors to support transformative…
Things are (literally) coming together over at our Ferntree Business Park Site! We can't wait to be able to open our doors to support transformative…
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I'm thrilled to highlight Google's commitment to a sustainable future through our Google Startups for Sustainable Development program. This…
I'm thrilled to highlight Google's commitment to a sustainable future through our Google Startups for Sustainable Development program. This…
Liked by Jacob Goodwin
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We're excited to share that Alt.Leather has been chosen to join the 2024 cohort of Climate Salad’s Climate Tech Global Growth Program. This program…
We're excited to share that Alt.Leather has been chosen to join the 2024 cohort of Climate Salad’s Climate Tech Global Growth Program. This program…
Liked by Jacob Goodwin
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This week I ate meat for the first time in five years - all thanks to the incredible work being done at Magic Valley. 🤯 I had the opportunity to…
This week I ate meat for the first time in five years - all thanks to the incredible work being done at Magic Valley. 🤯 I had the opportunity to…
Liked by Jacob Goodwin
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Great to chat with Dr. Leon Gettler about some of the demand drivers for Magic Valley's cultivated meat on Talking Business! 📈 Check out the full…
Great to chat with Dr. Leon Gettler about some of the demand drivers for Magic Valley's cultivated meat on Talking Business! 📈 Check out the full…
Liked by Jacob Goodwin
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